CAJ | 학술논문

急性脑血管病是目前死亡率最高的三大疾病之一，尤以缺血性脑血管病为最多见（约70%）。除高发病率、致死率及复发率外，由此引起的失语、痴呆、瘫痪等后遗症不仅使患者的生存质量下降，更给社会和家庭带来沉重负担。丹红注射液是由丹参、红花两味中药经合理组方、现代化生产工艺精制而成的复方提取液注射剂，其药理作用为活血化瘀、通脉疏络，具有改善血管缺血、缺氧，防止血小板聚集，降低血黏度，改善微循环障碍和血管代谢障碍等功能，本文就丹红注射液对脑缺血再灌注损伤干预作用的研究作一综述。
급성뇌혈관병시목전사망솔최고적삼대질병지일，우이결혈성뇌혈관병위최다견（약70%）。제고발병솔、치사솔급복발솔외，유차인기적실어、치태、탄탄등후유증불부사환자적생존질량하강，경급사회화가정대래침중부담。단홍주사액시유단삼、홍화량미중약경합리조방、현대화생산공예정제이성적복방제취액주사제，기약리작용위활혈화어、통맥소락，구유개선혈관결혈、결양，방지혈소판취집，강저혈점도，개선미순배장애화혈관대사장애등공능，본문취단홍주사액대뇌결혈재관주손상간예작용적연구작일종술。
Acute cerebrovascular disease is on of the three diseases which have highest mortality rate. The ischemic cerebrovascular disease is most common (about 70%). In spite of high rate of morbidity, fatality and recurrence, the sequelae caused by it, such as aphasias, dementia and paralysis, not only reduce the life quality of patients, but also place a huge burden on their family and society. Danhong injection is a compound extract injection composed with radix salvia and safflower carthamus by reasonable compatibility and modern production technique. Its pharmacological functions include activating blood circulation and resolving blood stasis, dredging meridians and smoothing collateral. It can improve the vascular ischemia and anoxia, prevent platelet aggregation, low blood viscosity and improve microcirculation disturbance and vascular metabolic disorders. This paper summarizes the intervention effect of Danhong injection on cerebral ischemia-reperfusion injury.