CAJ | 학술논문

目的：探讨创伤性脑损伤（TBI）后低钠血症的发生特点及其危险因素。方法回顾性分析我院136例中、重度TBI患者的临床资料，主要包括年龄、性别、损伤类型、GCS评分、手术、是否有脑水肿和颅底骨折等，并对上述因素与低钠血症的发生进行卡方检验和多因素Logistic回归分析。结果136例中、重度TBI患者中有56例发生低钠血症，经多因素Logistic回归分析，TBI后低钠血症的发生与患者的年龄、性别、损伤类型、是否开颅手术无关，而与患者的GCS评分、是否合并脑水肿或颅底骨折关系密切。结论 TBI患者如GCS≤8分、合并有脑水肿或颅底骨折，则易于发生低钠血症，需提前采取预防措施。
목적：탐토창상성뇌손상（TBI）후저납혈증적발생특점급기위험인소。방법회고성분석아원136례중、중도TBI환자적림상자료，주요포괄년령、성별、손상류형、GCS평분、수술、시부유뇌수종화로저골절등，병대상술인소여저납혈증적발생진행잡방검험화다인소Logistic회귀분석。결과136례중、중도TBI환자중유56례발생저납혈증，경다인소Logistic회귀분석，TBI후저납혈증적발생여환자적년령、성별、손상류형、시부개로수술무관，이여환자적GCS평분、시부합병뇌수종혹로저골절관계밀절。결론 TBI환자여GCS≤8분、합병유뇌수종혹로저골절，칙역우발생저납혈증，수제전채취예방조시。
Objective To investigate the incidence and etiological factors of hyponatremia following traumatic brain injury (TBI) and analyze the relationship between hyponatremia and the patient’s age, gender, type of injury, Glasgow coma scale (GCS), operation and computerized tomography (CT) scan of head. Methods Clinical data of 136 pa-tients with moderate or severe TBI in our hospital were analyzed retrospectively, including patient’s age, gender, type of injury, GCS, operation, brain edema and basal skull fracture. The relationship between clinical data and hyponatremia were analyzed statistically by Chi-square test and multivariate Logistic regression analysis. Results There were 56 pa-tients with hyponatremia in 136 patients (81 males) with moderate or severe TBI. Multivariate Logistic regression analysis showed that hyponatremia secondary to TBI was not associated with patient’s age, gender, type of injury and operation or not. However, there was a high correlation between hyponatremia following TBI and clinical characteristics of TBI at ear-ly stage, such as GCS, brain edema and basal skull fracture. Conclusions Patients with TBI is more likely to develop hy-ponatremia when they have the following clinical factors, such as GCS≤8, brain edema or basal skull fracture. Preven-tive measures should be given to these patients in advance.