当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
23期
142-143
,共2页
孟鲁司特%博利康尼%氨溴特罗%小儿哮喘
孟魯司特%博利康尼%氨溴特囉%小兒哮喘
맹로사특%박리강니%안추특라%소인효천
Montelukast%Bricanyl%Ambroxol%Clenbuterol
目的：探讨博利康尼与氨溴特罗分别联合孟鲁司特治疗小儿哮喘临床效果。方法选取万安县人民医院2010年5月～2012年5月收治的80例小儿哮喘患者随机均分为观察组与参考组（n=40），给予观察组患者博利康尼联合孟鲁司特治疗，给予参考组患者氨溴特罗联合孟鲁司特治疗，比较2组患者临床治疗效果、哮喘控制测试评分、不良反应发生率、复发率。结果观察组患者治疗总有效率为95%，参考组患者治疗总有效率为92.5%，比较差异无统计学意义，治疗后2组患儿哮喘测试评分分别为（20.13±2.56）分、（20.45±2.72）分，治疗4周时，2组患儿哮喘测试评分分别为（23.83±1.22）分、（23.57±1.16）分，比较差异无统计学意义。2组患者均未出现严重不良反应，3个随访期内，2组患儿各出现3例复发患儿，复发率为7.5%，比较差异无统计学意义。结论博利康尼与氨溴特罗分别联合孟鲁司特治疗小儿哮喘均具有良好效果，能够改善肺功能，安全有效。
目的：探討博利康尼與氨溴特囉分彆聯閤孟魯司特治療小兒哮喘臨床效果。方法選取萬安縣人民醫院2010年5月～2012年5月收治的80例小兒哮喘患者隨機均分為觀察組與參攷組（n=40），給予觀察組患者博利康尼聯閤孟魯司特治療，給予參攷組患者氨溴特囉聯閤孟魯司特治療，比較2組患者臨床治療效果、哮喘控製測試評分、不良反應髮生率、複髮率。結果觀察組患者治療總有效率為95%，參攷組患者治療總有效率為92.5%，比較差異無統計學意義，治療後2組患兒哮喘測試評分分彆為（20.13±2.56）分、（20.45±2.72）分，治療4週時，2組患兒哮喘測試評分分彆為（23.83±1.22）分、（23.57±1.16）分，比較差異無統計學意義。2組患者均未齣現嚴重不良反應，3箇隨訪期內，2組患兒各齣現3例複髮患兒，複髮率為7.5%，比較差異無統計學意義。結論博利康尼與氨溴特囉分彆聯閤孟魯司特治療小兒哮喘均具有良好效果，能夠改善肺功能，安全有效。
목적：탐토박리강니여안추특라분별연합맹로사특치료소인효천림상효과。방법선취만안현인민의원2010년5월～2012년5월수치적80례소인효천환자수궤균분위관찰조여삼고조（n=40），급여관찰조환자박리강니연합맹로사특치료，급여삼고조환자안추특라연합맹로사특치료，비교2조환자림상치료효과、효천공제측시평분、불량반응발생솔、복발솔。결과관찰조환자치료총유효솔위95%，삼고조환자치료총유효솔위92.5%，비교차이무통계학의의，치료후2조환인효천측시평분분별위（20.13±2.56）분、（20.45±2.72）분，치료4주시，2조환인효천측시평분분별위（23.83±1.22）분、（23.57±1.16）분，비교차이무통계학의의。2조환자균미출현엄중불량반응，3개수방기내，2조환인각출현3례복발환인，복발솔위7.5%，비교차이무통계학의의。결론박리강니여안추특라분별연합맹로사특치료소인효천균구유량호효과，능구개선폐공능，안전유효。
Objective To observe the clinical effect of bricanyl and ambroxol and clenbuterol combined with montelukast treating infantile asthma. Methods 80 children with infantile asthma treated in Wanan County People's Hospital from May 2010 to May 2012 were selected and divided into two groups randomly, the control group and the observation group, each group for 40 cases. The observation group was treated with bricanyl combined with montelukast, and the control group was treated with ambroxol and clenbuterol combined with montelukast. The clinical treatment effect, asthma control test score, incidence rate of adverse reactions and recurrence rate of two groups were compared. Results Patients in the observation group the total effective rate was 95%, the reference group the total effective rate was 92.5%, no significant difference, after treatment of 2 groups of children asthma test scores were (20.13 ± 2.56), (20.45 ± 2.72), 4 weeks of treatment, 2 groups of children with asthma score test respectively (23.83 ± 1.22), (23.57 ± 1.16), no significant difference. Serious adverse reactions were not found in patients in the 2 groups, 3 during the follow-up period, 2 groups of children with the appearance of 3 cases with recurrence, the recurrence rate was 7.5%, no significant difference. Conclusion Bricanyl and ambroxol and clenbuterol combined with montelukast treating infantile asthma not only has good efficacy, but also improves the lung functions, which is safe and effective.
