国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2012年
24期
1890-1893
,共4页
纤溶酶原激活物抑制物-1%肺血栓栓塞症%肺纤维化%支气管哮喘
纖溶酶原激活物抑製物-1%肺血栓栓塞癥%肺纖維化%支氣管哮喘
섬용매원격활물억제물-1%폐혈전전새증%폐섬유화%지기관효천
Plasminogen activator inhibitor-1%Pulmonary thromboembolism%Pulmonary fibrosis%Bronchial asthma
纤溶酶原激活物抑制物-1是丝氨酸蛋白酶抑制剂家族成员之一,是纤溶酶原激活物快速、专一、有效的生理抑制剂,可影响由组织型纤溶酶原激活物参与的纤溶过程,以及尿激酶型纤溶酶原激活物参与的生理病理条件下纤维蛋白溶解、细胞外基质循环、细胞迁移、组织修复、肿瘤浸润及转移等过程.
纖溶酶原激活物抑製物-1是絲氨痠蛋白酶抑製劑傢族成員之一,是纖溶酶原激活物快速、專一、有效的生理抑製劑,可影響由組織型纖溶酶原激活物參與的纖溶過程,以及尿激酶型纖溶酶原激活物參與的生理病理條件下纖維蛋白溶解、細胞外基質循環、細胞遷移、組織脩複、腫瘤浸潤及轉移等過程.
섬용매원격활물억제물-1시사안산단백매억제제가족성원지일,시섬용매원격활물쾌속、전일、유효적생리억제제,가영향유조직형섬용매원격활물삼여적섬용과정,이급뇨격매형섬용매원격활물삼여적생리병리조건하섬유단백용해、세포외기질순배、세포천이、조직수복、종류침윤급전이등과정.
Plasminogen activator inhibitor-1 (PAI-1) is one of the members of the family of serine protease inhibitors,is fast,specific,effective physiological inhibitor of plasminogen activator,can affect process of fibrinolysis involved by tissue-type plasminogen activator,as well as fibrinolysis,extracellular matrix loops,cell migration,tissue repair,tumor invasion and metastasis process involved by urokinasetype plasminogen activator under physiological and pathological conditions.