生物技术通讯
生物技術通訊
생물기술통신
LETTERS IN BIOTECHNOLOGY
2014年
4期
601-604
,共4页
国际非专利名称%中国药品通用名称%词干%聚乙二醇修饰%重组人粒细胞刺激因子
國際非專利名稱%中國藥品通用名稱%詞榦%聚乙二醇脩飾%重組人粒細胞刺激因子
국제비전리명칭%중국약품통용명칭%사간%취을이순수식%중조인립세포자격인자
International Nonproprietary Names%nomenclaturel steml PEGylation recombinant human granulo-cyte colony-stimulating factor
有越来越多的聚乙二醇修饰人粒细胞刺激因子研发上市。为适应这类制品的发展，中国药品通用名命名原则也需要不断更新修订。简要介绍了聚乙二醇修饰蛋白技术以及WHO国际非专利药品名（INN）命名委员会对这类制品的命名情况，讨论了我国对这类制品的药品通用命名原则和方法，建议对聚乙二醇化不同的修饰形式在名称上适当加以区分，并注意加强与INN命名委员会的交流合作。
有越來越多的聚乙二醇脩飾人粒細胞刺激因子研髮上市。為適應這類製品的髮展，中國藥品通用名命名原則也需要不斷更新脩訂。簡要介紹瞭聚乙二醇脩飾蛋白技術以及WHO國際非專利藥品名（INN）命名委員會對這類製品的命名情況，討論瞭我國對這類製品的藥品通用命名原則和方法，建議對聚乙二醇化不同的脩飾形式在名稱上適噹加以區分，併註意加彊與INN命名委員會的交流閤作。
유월래월다적취을이순수식인립세포자격인자연발상시。위괄응저류제품적발전，중국약품통용명명명원칙야수요불단경신수정。간요개소료취을이순수식단백기술이급WHO국제비전리약품명（INN）명명위원회대저류제품적명명정황，토론료아국대저류제품적약품통용명명원칙화방법，건의대취을이순화불동적수식형식재명칭상괄당가이구분，병주의가강여INN명명위원회적교류합작。
A lot of PEGylated granulocyte colony-stimulating factor have been approved. Therefore, the naming scheme of Chinese Approved Drug Name must be revised to adapting the development of PEGylated protein. In the article, author introduced the PEGylation technology and International Nonproprietary Names(INN) for this prod-ucts. The nomenclature for PEGylated protein in China was discussed. In "pegfilgrastim", "empegfilgrastim" and "li-pegfilgrastim" being assigned by INN expert committee, "em" and "li" are the identifiers to distinguish the PE-Gylation. The author proposed that proper identifiers would be added to Chinese Approved Drug Name of different PEGylation protein. In addition, the communication with INN committee should be strengthened.
