CAJ | 학술논문

目的：评价超顺磁性氧化铁（SPIO）与钆动态增强（Gd-DTPA）MRI对肝占位病变的诊断价值。方法回顾性分析30例肝占位病变的SPIO增强及Gd-DTPA动态增强MRI资料。结果 SPIO增强后T2WI良性病灶对应的增强前后肝脏的信号强度（SIL）和肝脏内局限性病变的信号强度（SIM ）均较平扫明显降低，而恶性病灶SIL较平扫明显降低，SPIO增强后SIM与平扫差异无统计学意义，病灶与正常肝组织的CNR较平扫明显增加；对于病灶直径≤2.0 cm的肝占位病变，SPIO增强扫描检出率高于Gd-DTPA ；且SPIO增强扫描的定性诊断率高于Gd-DTPA。结论 SPIO增强MRI可提高肝占位病变的临床诊断率，具有一定的可靠性。
목적：평개초순자성양화철（SPIO）여구동태증강（Gd-DTPA）MRI대간점위병변적진단개치。방법회고성분석30례간점위병변적SPIO증강급Gd-DTPA동태증강MRI자료。결과 SPIO증강후T2WI량성병조대응적증강전후간장적신호강도（SIL）화간장내국한성병변적신호강도（SIM ）균교평소명현강저，이악성병조SIL교평소명현강저，SPIO증강후SIM여평소차이무통계학의의，병조여정상간조직적CNR교평소명현증가；대우병조직경≤2.0 cm적간점위병변，SPIO증강소묘검출솔고우Gd-DTPA ；차SPIO증강소묘적정성진단솔고우Gd-DTPA。결론 SPIO증강MRI가제고간점위병변적림상진단솔，구유일정적가고성。
Objective To evaluate the value of SPIO and Gd-DTPA enhanced MRI in the diagnosis of liver lesions .Methods Gd-DTPA dynamic enhanced and SPIO-enhanced MRI findings in 30 patients with liver lesions were retrospectively analyzed . Results In SPIO-enhanced MRI ,the signal intensity of normal hepatie parenchyma was decreased in T 2WI while the CNR be-tween lesions and normal liver tissues signifieantly improved .For SPIO-enhanced MRI ,the rate of detection of hepatic lesions (≤2.0 cm)and the accuracy of characteristic diagnosis was higher than that of Gd-DTPA-enhanced MRI .Conclusion SPIO-en-hanced M RI can increase the diagnosis rate of liver lesions .