CAJ | 학술논문

目的：观察益肾活血通关汤联合非那雄胺片治疗老年良性前列腺增生（BHP）的临床疗效。方法将110例BHP老年患者随机分为2组，对照组52例予非那雄胺片治疗，治疗组58例在对照组治疗基础上加益肾活血通关汤治疗。治疗6周后评定疗效，比较2组患者治疗前后前列腺症状评分（ I-PSS评分）、生活质量指数、最大尿流率（ MFR ）、膀胱残余尿量及前列腺体积变化情况。结果治疗组总有效率（84．48％）优于对照组（69．23％，P＜0．05）。与本组治疗前比较，2组治疗后I-PSS评分、生活质量指数降低，膀胱残余尿量减少，前列腺体积缩小，比较差异均有统计学意义（P＜0．05），且2组组间比较差异有统计学意义（ P＜0．05）。结论益肾活血通关汤联合非那雄胺片治疗老年BHP，能有效改善临床症状，提高患者生活质量，副作用少，安全显效，值得临床推广应用。
목적：관찰익신활혈통관탕연합비나웅알편치료노년량성전렬선증생（BHP）적림상료효。방법장110례BHP노년환자수궤분위2조，대조조52례여비나웅알편치료，치료조58례재대조조치료기출상가익신활혈통관탕치료。치료6주후평정료효，비교2조환자치료전후전렬선증상평분（ I-PSS평분）、생활질량지수、최대뇨류솔（ MFR ）、방광잔여뇨량급전렬선체적변화정황。결과치료조총유효솔（84．48％）우우대조조（69．23％，P＜0．05）。여본조치료전비교，2조치료후I-PSS평분、생활질량지수강저，방광잔여뇨량감소，전렬선체적축소，비교차이균유통계학의의（P＜0．05），차2조조간비교차이유통계학의의（ P＜0．05）。결론익신활혈통관탕연합비나웅알편치료노년BHP，능유효개선림상증상，제고환자생활질량，부작용소，안전현효，치득림상추엄응용。
Objective To investigate the clinical effect of Yishen Huoxue Tongguan decoction combined withFinasterideTabletsonsenilebenignprostatichyperplasia(BHP).Methods 110BHPpatientswererandomly divided into two groups .52 cases in control group were treated by Finasteride Tablets .58 patients in treatment group were given Yishen Huoxue Tongguan decoction combined with Finasteride Tablets .After treatment of 6 weeks interna-tional prostate symptom score ( IPSS) , index of the quality of life , maximum flow rate ( MFR) , the bladder residual urine volume and change of prostate volume were compared in two groups .Results The total effective rate in treat-ment group (84.48%) was superior to that in control group (69.23%, P <0.05).IPSS and index of the quality of life were decreased after treatment in two groups .Index of the quality of life , MFR and the bladder residual urine vol-ume after treatment were decreased in two groups ( P <0 .05 ) .Conclusion Yishen Huoxue Tongguan decoction combined with Finasteride Tablets on senile prostatic hyperplasia can effectively improve the clinical symptoms , im-prove patient quality of life , less side effects , safety powerfully , worthy of clinical popularization and application .