CAJ | 학술논문

目的：应用二维斑点追踪成像（STI）技术检测2型糖尿病患者左心室收缩功能的早期改变，并探讨其临床应用价值。方法2型糖尿病患者（左心室射血分数≥50%）60例，分为单纯糖尿病组（A组）30例和糖尿病合并左心室壁肥厚组（B组）30例；正常对照组30例。分别测量左心室长轴及短轴各节段收缩期纵向、径向、圆周峰值应变，并计算其平均值。结果与对照组相比，糖尿病组收缩期纵向、圆周峰值应变及平均应变均明显减低（P＜0.05），B组低于A组（P＜0.05）。与对照组比较，糖尿病组径向峰值应变及平均应变亦减低，但差异无统计学意义（P＞0.05）。结论 STI技术可早期检测糖尿病患者左心室心肌局部收缩功能异常。
목적：응용이유반점추종성상（STI）기술검측2형당뇨병환자좌심실수축공능적조기개변，병탐토기림상응용개치。방법2형당뇨병환자（좌심실사혈분수≥50%）60례，분위단순당뇨병조（A조）30례화당뇨병합병좌심실벽비후조（B조）30례；정상대조조30례。분별측량좌심실장축급단축각절단수축기종향、경향、원주봉치응변，병계산기평균치。결과여대조조상비，당뇨병조수축기종향、원주봉치응변급평균응변균명현감저（P＜0.05），B조저우A조（P＜0.05）。여대조조비교，당뇨병조경향봉치응변급평균응변역감저，단차이무통계학의의（P＞0.05）。결론 STI기술가조기검측당뇨병환자좌심실심기국부수축공능이상。
Objective To investigate the clinical value of two-dimensional speckle tracking imaging in assessment of early change of left ventricular (LV) systolic function of type 2 diabetes mellitus (T2DM). Methods The study included 30 T2DM with diabetes mellitus only (groups A), 30 T2DM with both diabetes and left ventricular hypertrophy (groups B), and 30 normal controls. The LV systolic peak longitudinal, radial, circumferential strain of each plane were measured, and average peak strain were assessed. Results Peak longitudinal, circumferential strain and average peak strain in both T2DM groups (A, B) were significantly reduced than that of controls (P<0.05), and those in group B were lower than in group A (P<0.05). There were no significant difference of peak radial strain and average peak strain among the three groups(P>0.05). Conclusion Two-dimensional speckle tracking imaging could be used to identify the early change of LV local systolic function in T2DM.