CAJ | 학술논문

目的：观察乌司他丁干预曲张大隐静脉改良腔内激光治疗术术后的疗效，并进行健康相关生命质量分析，进一步探讨曲张静脉改良术式术后并发症的治疗。方法大隐静脉曲张患者50例，经术前查体及多普勒超声检查排除严重深静脉反流等，应用乌司他丁加改良激光治疗术式操作；调取2009年5月至2010年8月应用传统激光治疗术式操作的50例患者作为对照组；观察2组术后3、12个月患者术后复发情况并据SF-36进行健康相关生命质量分析。结果患者术后3、12个月健康程度、健康情况、生理状态、躯体角色、心理情况、情感角色、疼痛程度、精神状态、社会角色、健康状态差异及术后复发差异无统计学意义（ P ＞0排．05），术后3个月治疗组疼痛影响2（1）、对照组2．5（1），差异有统计学意义（ P ＜0．05）；患者对腔内激光治疗术两种术式均表示满意，治疗组2（1），对照组2（1），差异有统计学意义（ P ＝0．12）；术后2组复发率（12个月）对照组4．84％，治疗组1．49％差异有统计学意义（ P ＝0．3505）。结论患者在对两种治疗方式的选择上表现较为一致，术后3、12个月复发率未表现出差异，而乌司他丁加改良腔内激光治疗术在术后疼痛的影响上要低于传统手术，具有优势。
목적：관찰오사타정간예곡장대은정맥개량강내격광치료술술후적료효，병진행건강상관생명질량분석，진일보탐토곡장정맥개량술식술후병발증적치료。방법대은정맥곡장환자50례，경술전사체급다보륵초성검사배제엄중심정맥반류등，응용오사타정가개량격광치료술식조작；조취2009년5월지2010년8월응용전통격광치료술식조작적50례환자작위대조조；관찰2조술후3、12개월환자술후복발정황병거SF-36진행건강상관생명질량분석。결과환자술후3、12개월건강정도、건강정황、생리상태、구체각색、심리정황、정감각색、동통정도、정신상태、사회각색、건강상태차이급술후복발차이무통계학의의（ P ＞0배．05），술후3개월치료조동통영향2（1）、대조조2．5（1），차이유통계학의의（ P ＜0．05）；환자대강내격광치료술량충술식균표시만의，치료조2（1），대조조2（1），차이유통계학의의（ P ＝0．12）；술후2조복발솔（12개월）대조조4．84％，치료조1．49％차이유통계학의의（ P ＝0．3505）。결론환자재대량충치료방식적선택상표현교위일치，술후3、12개월복발솔미표현출차이，이오사타정가개량강내격광치료술재술후동통적영향상요저우전통수술，구유우세。
Objectives To observe the therapeutic effect of ulinastatin intravenous infusion combined with improved endovenous laser ablation (IEVLA) on great saphenous vein varicosity (GSVV),and to analyze health-related life quality. Methods Fifty patients with GSVV who were examined by Doppler ultrasonography to exclude severe deep vein countercurrent were treated by ulinastatin intravenous infusion combined with improved endovenous laser ablation ( trial group) ,and the other 50 patients who were admitted in our department between May 2009 and August 2010 were treated by traditional laser therapy ( control group ).The relapse condition at 3,12 months after the operation was observed for both groups,and the health-related life quality analysis was performed according to SF-36.Results There were no significant differences in the health levels,health condition, physiological state,body functions,psychological condition,feeling role,pain degree,mental status,social role,sanitation and relapse after operation at 3 months,12 months after operation,as compared with those before operation ( P >0.05).However there was a significant difference in the pain degree between control group and trial group ( P <0.05).There was no significant difference in the satisfactory degree of patients to IEVLA operation between two groups ( P >0.05),and there was no significant difference in the relapse rate after operation between two groups ( P >0.05).Conclusion The patients with great saphenous vein varicosity have basically same selection for the two therapy ways , and there is no significant difference in relapse rate at 3 months,12 months after operation between two kinds of treatment methods , however , the effect of ulinastatin intravenous infusion combined with improved endovenous laser ablation on postoperative pain is less than that in traditional operation .