CAJ | 학술논문

目的：初步探讨不同饮用水对小鼠脏器系数及血糖水平的影响。方法分别测定纯净水、自来水、净化水、高偏硅酸天然矿泉水的偏硅酸含量。将80只ICR小鼠随机分为4组,每组各20只,雌雄各半,分别用纯净水(对照组)、自来水、净化水和矿泉水喂养,90 d后眼球取血,测定空腹血糖值及小鼠体重、脏器系数。结果4种饮用水的偏硅酸含量差异有统计学意义(P<0.05),含量高低依次为纯净水<净化水<自来水<矿泉水。与纯净水组比较,净化水组的小鼠心脏系数明显降低(P<0.05)；矿泉水组雌性小鼠的空腹血糖水平也明显降低(P<0.05)。结论不同水质可能对小鼠心脏系数及雌性小鼠血糖代谢有影响。
목적：초보탐토불동음용수대소서장기계수급혈당수평적영향。방법분별측정순정수、자래수、정화수、고편규산천연광천수적편규산함량。장80지ICR소서수궤분위4조,매조각20지,자웅각반,분별용순정수(대조조)、자래수、정화수화광천수위양,90 d후안구취혈,측정공복혈당치급소서체중、장기계수。결과4충음용수적편규산함량차이유통계학의의(P<0.05),함량고저의차위순정수<정화수<자래수<광천수。여순정수조비교,정화수조적소서심장계수명현강저(P<0.05)；광천수조자성소서적공복혈당수평야명현강저(P<0.05)。결론불동수질가능대소서심장계수급자성소서혈당대사유영향。
Objective To explore the effect of different drinking water on organ coefficent and blood glucose in mice. Methods Metasilicic acid content was measured in the pure water,tap water,filtered tap-water and high metasilicate mineral water respectively.80 ICR mice (half male and half female) were randomly divided into the four groups and fed with pure water (the control group),tap water,filtered tap-water and mineral water respectively.After 90 days, blood samples were taken from the eyeballs of mice. Then the fasting blood glucose,body weight and organ coefficient were analyzed. Results Metasilicic acid content of four kinds of drinking water had a statistical difference (P<0.05), which were pure water<filtered tap-water<tap water<mineral water.Compared with the control group,a significant decline in cardiac coefficient of mice was observed in filtered tap-water group (P<0.05),and the same significant decline in fasting blood glucose of female mice was observed in the mineral water group (P<0.05). Conclusion Different water quality may cause biological effects on cardiac coefficient of mice and glucose metabolism in female mice.