广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2014年
15期
155-157,169
,共4页
硝基呋喃代谢物%液相色谱-串联质谱法%水产品%检测%优化%使用状况统计
硝基呋喃代謝物%液相色譜-串聯質譜法%水產品%檢測%優化%使用狀況統計
초기부남대사물%액상색보-천련질보법%수산품%검측%우화%사용상황통계
nitrofuran metabolites%liquid chromatography tandem mass spectrometry%aquatic products%detection%optimization%usage statistics
硝基呋喃类化合物及其代谢物具有强毒性和强致癌作用，本文研究了液相色谱-串联质谱法检测水产中4类硝基呋喃类物质代谢物的方法。结果表明，方法线性范围0.25～10.0μg/L，线性相关系数大于0.9992，在0.50、1.0、5.0μg/kg 三个添加水平回收率82％～110％，相对标准偏差2.7％～10％。分析某区水产中硝基呋喃类药物使用状况： AOZ和SEM使用最普遍， AMOZ使用较少， AHD未发现检出样品。
硝基呋喃類化閤物及其代謝物具有彊毒性和彊緻癌作用，本文研究瞭液相色譜-串聯質譜法檢測水產中4類硝基呋喃類物質代謝物的方法。結果錶明，方法線性範圍0.25～10.0μg/L，線性相關繫數大于0.9992，在0.50、1.0、5.0μg/kg 三箇添加水平迴收率82％～110％，相對標準偏差2.7％～10％。分析某區水產中硝基呋喃類藥物使用狀況： AOZ和SEM使用最普遍， AMOZ使用較少， AHD未髮現檢齣樣品。
초기부남류화합물급기대사물구유강독성화강치암작용，본문연구료액상색보-천련질보법검측수산중4류초기부남류물질대사물적방법。결과표명，방법선성범위0.25～10.0μg/L，선성상관계수대우0.9992，재0.50、1.0、5.0μg/kg 삼개첨가수평회수솔82％～110％，상대표준편차2.7％～10％。분석모구수산중초기부남류약물사용상황： AOZ화SEM사용최보편， AMOZ사용교소， AHD미발현검출양품。
Nitrofuran compounds and their metabolites were toxic and carcinogenic effect , and the method of liquid chromatography-tandem mass spectrometry detection of aquatic 4 nitrofurans metabolite was studied.The result showed that linear range of the method was 0.25~10.0μg/kg, the linear correlation coefficient was greater than 0.999 2, 0.50, 1 , 5 μg/kg three addition level of recovery was 82%~110%, and the relative standard deviation was 2.7%~10%.Analysis on the utilization situation of nitrofuran drugs in aquaculture showed that AOZ and SEM was the most common use, AMOZ was used less, and AHD was not found in samples.
