解剖学报
解剖學報
해부학보
ACTA ANATOMICA SINICA
2014年
4期
573-577
,共5页
杨鑫%孙红兵%骆继怀%哈飞%张子龙
楊鑫%孫紅兵%駱繼懷%哈飛%張子龍
양흠%손홍병%락계부%합비%장자룡
Y-STR基因座%遗传距离%分子人类学%兰州%汉族
Y-STR基因座%遺傳距離%分子人類學%蘭州%漢族
Y-STR기인좌%유전거리%분자인류학%란주%한족
Y-STR loci%Genetic distance%Molecular anthropology%Lanzhou%Han population
目的:探讨兰州汉族等26个人群Y-STR基因座遗传关系。方法研究得到500名无关兰州汉族个体的Y-STR基因座基因频率,同时收集其他25个人群相同Y-STR基因座基因频率,应用亲缘系数比较分析这26个人群间的遗传距离并绘制系统树。结果汉族人群中以北京汉族、山西汉族、内蒙古汉族和与兰州汉族的遗传关系最接近;少数民族人群中以内蒙古蒙古族与兰州汉族的遗传关系最接近;马来西亚马来人和马来西亚印度人与其他人群遗传关系最远而单独列支。结论利用Y-STR基因座的等位基因频率研究不同人群之间的遗传距离,结果与其他分子人类学结论接近或吻合,表明不同人群之间的遗传关系与地域、起源和进化的关系密切。
目的:探討蘭州漢族等26箇人群Y-STR基因座遺傳關繫。方法研究得到500名無關蘭州漢族箇體的Y-STR基因座基因頻率,同時收集其他25箇人群相同Y-STR基因座基因頻率,應用親緣繫數比較分析這26箇人群間的遺傳距離併繪製繫統樹。結果漢族人群中以北京漢族、山西漢族、內矇古漢族和與蘭州漢族的遺傳關繫最接近;少數民族人群中以內矇古矇古族與蘭州漢族的遺傳關繫最接近;馬來西亞馬來人和馬來西亞印度人與其他人群遺傳關繫最遠而單獨列支。結論利用Y-STR基因座的等位基因頻率研究不同人群之間的遺傳距離,結果與其他分子人類學結論接近或吻閤,錶明不同人群之間的遺傳關繫與地域、起源和進化的關繫密切。
목적:탐토란주한족등26개인군Y-STR기인좌유전관계。방법연구득도500명무관란주한족개체적Y-STR기인좌기인빈솔,동시수집기타25개인군상동Y-STR기인좌기인빈솔,응용친연계수비교분석저26개인군간적유전거리병회제계통수。결과한족인군중이북경한족、산서한족、내몽고한족화여란주한족적유전관계최접근;소수민족인군중이내몽고몽고족여란주한족적유전관계최접근;마래서아마래인화마래서아인도인여기타인군유전관계최원이단독렬지。결론이용Y-STR기인좌적등위기인빈솔연구불동인군지간적유전거리,결과여기타분자인류학결론접근혹문합,표명불동인군지간적유전관계여지역、기원화진화적관계밀절。
Objective To study the genetic relationship of the Y chromosomal short tandem repeat gene loci in Lanzhou Han population and other 25 populations .Methods The frequency of alleles of Y-STRloci was obtained from a sample of 500 unrelated individuals living in Lanzhou City , and other 25 populations in different areas collected from the published data were used to calculate the genetic similarity coefficient and genetic distance .Phylogenetic trees based on the genetic distance were established .Results Populations of Lanzhou , Beijing, Shanxi and Inner Mongolia were in an identical cluster .Compared with minorities , the genetic distance between Lanzhou Han population and Inner Mongolia Mongolian population was dramatically smaller from other subpopulations .The populations in Malays and Indians were far from the other groups .Conclusion The Y-STR gene frequency distribution in 26 populations has identified differentiation in race, clime and evolution, and it is basically identical with the classification of human races which is similar to or according with other molecular anthropology research conclusions .