CAJ | 학술논문

目的：分析动态脉压、动态脉压指数与高血压病患者心房颤动（ Af ）发生的关系。方法原发性高血压患者368例，其中伴Af的患者81例（高血压病伴Af组），余无Af发作史的患者287例（高血压病不伴Af组），并将上述患者根据24 h动态脉压（24 h APP）分为＜60 mmHg组和≥60 mmHg组，根据脉压指数分为＜0.5组和≥0.5组。分析比较各组Af发生情况、临床特征，及其与动态脉压和动态脉压指数的相关性。结果高血压病伴Af组24 h APP、动态脉压指数明显高于高血压病不伴Af组（ P＜0.01）。24 h APP≥60 mmHg组，24 h收缩压、动态脉压指数、左房前后径明显高于24 h APP＜60 mmHg组（ P＜0.05）。动态脉压指数≥0.5组24 h收缩压、24 h APP、左房前后径明显高于脉压指数＜0.5组（ P＜0.05）。 Spearman相关分析显示高血压病患者Af发生率与24 h APP、动态脉压指数呈正相关（ r分别为0.783和0.796，均P＜0.01）。结论高血压病患者Af发生率随动态脉压、动态脉压指数升高而增高。
목적：분석동태맥압、동태맥압지수여고혈압병환자심방전동（ Af ）발생적관계。방법원발성고혈압환자368례，기중반Af적환자81례（고혈압병반Af조），여무Af발작사적환자287례（고혈압병불반Af조），병장상술환자근거24 h동태맥압（24 h APP）분위＜60 mmHg조화≥60 mmHg조，근거맥압지수분위＜0.5조화≥0.5조。분석비교각조Af발생정황、림상특정，급기여동태맥압화동태맥압지수적상관성。결과고혈압병반Af조24 h APP、동태맥압지수명현고우고혈압병불반Af조（ P＜0.01）。24 h APP≥60 mmHg조，24 h수축압、동태맥압지수、좌방전후경명현고우24 h APP＜60 mmHg조（ P＜0.05）。동태맥압지수≥0.5조24 h수축압、24 h APP、좌방전후경명현고우맥압지수＜0.5조（ P＜0.05）。 Spearman상관분석현시고혈압병환자Af발생솔여24 h APP、동태맥압지수정정상관（ r분별위0.783화0.796，균P＜0.01）。결론고혈압병환자Af발생솔수동태맥압、동태맥압지수승고이증고。
Objective To investigate the relationship between ambulatory pulse pressure (APP),ambulatory pulse pressure index and atrial fibrillation (Af) in hypertension patients.Methods Three hundred and sixty-eight patients with primary hypertension were enrolled in this study.There were 81 patients with Af (Af group) and 287 without Af (non-Af group).According to 24 h APP,the patients were divided into <60 mmHg group and ≥60 mmHg group.According to APP index,the patients were divided into <0.5 group and≥0.5 group.The incidence of atrial fibrillation ,clinical characteristics and their relationships with APP and ambulatory pulse pressure index were compared among the groups .Results The 24 h APP and APP index in the Af group were significantly higher than that in the non-Af group (P<0.01).The 24 h SBP,APP index and the left atrium diameter in the 24 h APP≥60 mmHg group were significantly higher than that in the AP P<60 mmHg group (P<0.05).The 24 h SBP,24 h APP and the left atrium diameter in the APP index ≥0.5 group were significantly higher than that in the APP index <0.5 group ( P<0.05 ) .Spearman correlation analysis showed that incidence of hypertension in patients with atrial fibrillation was positively correlated with 24 h APP and APP index ( r =0.783 ,r =0.796 ,P<0.01 ) .Conclusion Incidence of atrial fibrillation in hypertension patients is increased with rising APP and APP index.