国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2013年
5期
651-654
,共4页
张新%王晓慧%何泳%彭清平
張新%王曉慧%何泳%彭清平
장신%왕효혜%하영%팽청평
尿毒症%肠道营养%透析
尿毒癥%腸道營養%透析
뇨독증%장도영양%투석
Uremia%Enteral Nutrition%Dialysis
目的 研究透析中肠内营养对老年尿毒症患者营养状态的影响.方法 选择病情稳定透析的老年患者24例,每次透析中经口给予含高热量、高蛋白的营养液250mL作为营养干预,观察2个月,进行相关指标测量.选取同期常规透析、年龄性别及营养状况等相匹配的老年患者28例作为对照.结果 研究组在2个月后握力由(25.2±2.8)kg增加至(26.8±2.5)kg,差异有统计学意义(P＜0.05)；与对照组(24.6±2.8)kg差异也有统计学意义(P＜0.01).研究组血清白蛋白、前白蛋白显著增加,分别为(35.0±2.2)g/L vs(36.5±1.3)g/L(P＜0.01)、(269.1±32.1) g/L vs (295.8±29.7)g/L(P＜0.01),且分别与对照组(35.7±1.7)g/L、(265.9±27.8)g/L比较也有统计学意义(P＜0.05、P＜0.01)；而日常蛋白质、热量摄入量及血钾、血磷较对照组比较差异无统计学意义.结论 透析中经口补充高蛋白、高热量肠内营养液能在短期内显著升高血清白蛋白、前白蛋白水平,并增加患者握力,较好地改善患者营养状态,是一种可行性、更符合生理的、价廉的营养不良干预措施,具有良好的应用前景.
目的 研究透析中腸內營養對老年尿毒癥患者營養狀態的影響.方法 選擇病情穩定透析的老年患者24例,每次透析中經口給予含高熱量、高蛋白的營養液250mL作為營養榦預,觀察2箇月,進行相關指標測量.選取同期常規透析、年齡性彆及營養狀況等相匹配的老年患者28例作為對照.結果 研究組在2箇月後握力由(25.2±2.8)kg增加至(26.8±2.5)kg,差異有統計學意義(P＜0.05)；與對照組(24.6±2.8)kg差異也有統計學意義(P＜0.01).研究組血清白蛋白、前白蛋白顯著增加,分彆為(35.0±2.2)g/L vs(36.5±1.3)g/L(P＜0.01)、(269.1±32.1) g/L vs (295.8±29.7)g/L(P＜0.01),且分彆與對照組(35.7±1.7)g/L、(265.9±27.8)g/L比較也有統計學意義(P＜0.05、P＜0.01)；而日常蛋白質、熱量攝入量及血鉀、血燐較對照組比較差異無統計學意義.結論 透析中經口補充高蛋白、高熱量腸內營養液能在短期內顯著升高血清白蛋白、前白蛋白水平,併增加患者握力,較好地改善患者營養狀態,是一種可行性、更符閤生理的、價廉的營養不良榦預措施,具有良好的應用前景.
목적 연구투석중장내영양대노년뇨독증환자영양상태적영향.방법 선택병정은정투석적노년환자24례,매차투석중경구급여함고열량、고단백적영양액250mL작위영양간예,관찰2개월,진행상관지표측량.선취동기상규투석、년령성별급영양상황등상필배적노년환자28례작위대조.결과 연구조재2개월후악력유(25.2±2.8)kg증가지(26.8±2.5)kg,차이유통계학의의(P＜0.05)；여대조조(24.6±2.8)kg차이야유통계학의의(P＜0.01).연구조혈청백단백、전백단백현저증가,분별위(35.0±2.2)g/L vs(36.5±1.3)g/L(P＜0.01)、(269.1±32.1) g/L vs (295.8±29.7)g/L(P＜0.01),차분별여대조조(35.7±1.7)g/L、(265.9±27.8)g/L비교야유통계학의의(P＜0.05、P＜0.01)；이일상단백질、열량섭입량급혈갑、혈린교대조조비교차이무통계학의의.결론 투석중경구보충고단백、고열량장내영양액능재단기내현저승고혈청백단백、전백단백수평,병증가환자악력,교호지개선환자영양상태,시일충가행성、경부합생리적、개렴적영양불량간예조시,구유량호적응용전경.
Objectives To study the influence of intradialytic enteral nutrition on malnutrition status in elderly patients with uremia.Methods Stable pathogenetic status elderly patients with Maintenance hemodialysis were selected.24 patients received 250ml enteral nutrient solution with 429Kcal calorie and 18.2g protein during dialysis therapy and 35 patients received conwentional hemodialysis(no nutrition support during dialysis) as control.All patients were observed for 2 months.The nutrition status of these patients on various aspects which concluded physical measeurements,laboratory tests,and dietary record at baseline (0 month) and esit (2 months) were recorded.Results There were no differences in age,sex,body weihgt,primary diseases,dietary intake,and main biochemical indicators between two groups.The body weight,mid-upper arm circumference (MAC),and triceps skinfold thickness (TSF) increased at esit point,but no statistical difference compared with the control group.Hand grip strength (HGS) increased significantly from (25.2 ±2.8)to(26.8 ±2.5)kg(P ＜0.05).Compared with the control group(24.6 ± 2.8) kg,there was a significant difference (P ＜ 0.01).Serum albumin and serum prealbumin increased significantly in the study group,(35.0±2.2)g/L vs(36.5 ±1.3)g/L(P ＜0.01),(269.1 ±32.1)g/L vs (295.8 ± 29.7) g/L(P ＜ 0.01),respectively.Compared with the control group(35.7 ± 1.7) g/L,(265.9±27.8) g/L,respectively,there were significant differences(P ＜ 0.05,P ＜ 0.01).But there were significant differences in the daily intake of protein,calories,potassium and blood phosphorus between two groups.In the study group,all patients are well tolerated to intradialytic enteral nutrition.Conclusions Supplying enteral nutrient solution with high calorie and high protein during dialysis can evaluate serum albumin,serum prealbumin and hand grip strength evidently in a short time,and then improve patients'nutritional state.The oral nutritional supplementation was feasible,more physiologic and affordable.It is a promising intervention measure of malnutrition.
