CAJ | 학술논문

目的：探讨甲亢合并周期性麻痹的临床特点，减少漏诊、误诊的发生。方法回顾性分析26例甲亢合并周期性麻痹患者的临床资料。结果患者经补钾后1～18 h病情迅速缓解，并予正规抗甲状腺药物治疗后22例甲功恢复正常，2例反复发作2次，经调整抗甲状腺药物后甲功恢复正常，2例因口服药出现不良反应改131 I治疗甲功恢复正常。26例随访6个月～1年内无周期性麻痹复发。结论甲亢合并周期性麻痹补钾治疗后症状迅速改善，积极有效控制甲亢是预防复发的关键，同时注意避免饱餐、感染、过度劳累、静脉输入高渗葡萄糖等诱发因素。
목적：탐토갑항합병주기성마비적림상특점，감소루진、오진적발생。방법회고성분석26례갑항합병주기성마비환자적림상자료。결과환자경보갑후1～18 h병정신속완해，병여정규항갑상선약물치료후22례갑공회복정상，2례반복발작2차，경조정항갑상선약물후갑공회복정상，2례인구복약출현불량반응개131 I치료갑공회복정상。26례수방6개월～1년내무주기성마비복발。결론갑항합병주기성마비보갑치료후증상신속개선，적겁유효공제갑항시예방복발적관건，동시주의피면포찬、감염、과도로루、정맥수입고삼포도당등유발인소。
Objective To investigate the clinical featurs of hyperthyroidism patients with periodic paralysis in order to dearease the rate of missed diagnosis and misdiagnosis .Methods A retrospective analysis of the clinical data was performed of 26 patients with hyperthyroidism complicated by periodic paralysis .Results Within 1to 18 h after potassium treatment , the patients′symptoms and signs quickly relieved , and after antithyroid drug treatment thy-roid function returned to normal in 22 patients.Two patients experienced 2 times of recurrent attacks and their thyroid function returned to normal after adjusting antithyroid drug .Due to adverse reaction of oral drugs ,2 patients were trea-ted with 131 I treatment instead of oral drugs and their thyroid function returned to normal after 131 I treatment.Within 6 to 12 months of follow-up,no recurrence of periodic paralysis appeared in 26 patients.Conclusion For patients with hyperthyroidism complicated by periodic paralysis , potassium supplementation can rapidly improve their symptoms;active and effective antithyroid drugs treatment is key to preventing recurrence ;at the same time , it is necessary to a-void the predisposing factors such as overeat ingestion , infection, excessive exertion , and intravenous infusion of hy-pertonic glucose and so on ,in order to prevent recurrence .