CAJ | 학술논문

目的：建立了饮料、牛奶和奶粉中双酚A及15种邻苯二甲酸酯的高效液相色谱-串联质谱分析方法。方法样品经甲醇提取, C18色谱柱分离后,采用串联四极杆质谱电喷雾电离源正负离子切换多反应离子监测模式检测。结果双酚A及15种邻苯二甲酸酯在各自的线性范围内线性关系良好,相关系数均不低于0.9900,定量下限为10μg/kg,低、中、高3个加标水平下平均回收率为61.1%~129.5%,相对标准偏差为1.13%~22.12%。结论该方法具有前处理简单、灵敏度高的优点,适用于饮料、牛奶及奶粉中双酚A及15种邻苯二甲酸酯残留的确证和定量检测。
목적：건립료음료、우내화내분중쌍분A급15충린분이갑산지적고효액상색보-천련질보분석방법。방법양품경갑순제취, C18색보주분리후,채용천련사겁간질보전분무전리원정부리자절환다반응리자감측모식검측。결과쌍분A급15충린분이갑산지재각자적선성범위내선성관계량호,상관계수균불저우0.9900,정량하한위10μg/kg,저、중、고3개가표수평하평균회수솔위61.1%~129.5%,상대표준편차위1.13%~22.12%。결론해방법구유전처리간단、령민도고적우점,괄용우음료、우내급내분중쌍분A급15충린분이갑산지잔류적학증화정량검측。
Objective A method for the simultaneous determination of bisphenol A (BPA) and fifteen phthalate esters (PAEs) by high performance liquid chromatography-tandem mass spectrometry was established. Methods The samples were extracted by methanol. The target compounds were separated by C18 column and detected by MS/MS system with eletrospray ionization (ESI) positive and negative ion mode under multiple reaction monitoring (MRM) mode. Results High correlation coefficients (r≥0.9900) of sixteen compounds were obtained within their respective linear ranges. The LOQ of BPA and 15 PAEs was 10 μg/kg. The recoveries ranged from 61.1%~129.5%, with the relative standard deviations of 1.13%~22.12%. Conclusion This method is suitable for the identification and quantification of PAEs and BPA in beverage, milk and milk powder with advantages of simple pretreatment, good purification and high sensitivity.