世界中西医结合杂志
世界中西醫結閤雜誌
세계중서의결합잡지
WORLD JOURNAL OF TRADITIONAL CHINESE AND WESTERN MEDICINE
2014年
8期
873-875
,共3页
脑白质病变%磁共振%临床特点%回顾性研究
腦白質病變%磁共振%臨床特點%迴顧性研究
뇌백질병변%자공진%림상특점%회고성연구
Leukodystrophy%MRI%Clinical Features%Retrospective Study
目的：研究脑白质病变的影像学改变及临床特点。方法回顾性纳入60～85岁行MRI检查示脑白质高信号改变的患者，回顾其影像学资料、临床资料，总结归纳脑白质病变的类型、严重程度，病史、认知与情绪评价结果，诊断等。结果脑白质病变类型以1型、2型为主，分别占总例数的47．45％、31．21％。病变程度均以轻度为主：脑室周围白质轻度改变占57．64％，脑深部白质轻度改变占68．79％。病史提示56．69％患高血压病，28．34％患脑卒中，29．30％患糖尿病。57．96％患者存在认知功能障碍；12．42％患者存在抑郁。66例脑梗死，42例阿尔兹海默病，88例血管性痴呆。中医诊断为“痴呆”患者以肾精亏虚（脑髓空虚）为主，占58．27％。结论脑白质病变影像学以轻中度改变为主，其发病可能与高血压、卒中、糖尿病等有关，其病变程度可能与认知功能下降有关，痴呆患者中医证型以肾精亏虚（脑髓空虚）型为主。
目的：研究腦白質病變的影像學改變及臨床特點。方法迴顧性納入60～85歲行MRI檢查示腦白質高信號改變的患者，迴顧其影像學資料、臨床資料，總結歸納腦白質病變的類型、嚴重程度，病史、認知與情緒評價結果，診斷等。結果腦白質病變類型以1型、2型為主，分彆佔總例數的47．45％、31．21％。病變程度均以輕度為主：腦室週圍白質輕度改變佔57．64％，腦深部白質輕度改變佔68．79％。病史提示56．69％患高血壓病，28．34％患腦卒中，29．30％患糖尿病。57．96％患者存在認知功能障礙；12．42％患者存在抑鬱。66例腦梗死，42例阿爾玆海默病，88例血管性癡呆。中醫診斷為“癡呆”患者以腎精虧虛（腦髓空虛）為主，佔58．27％。結論腦白質病變影像學以輕中度改變為主，其髮病可能與高血壓、卒中、糖尿病等有關，其病變程度可能與認知功能下降有關，癡呆患者中醫證型以腎精虧虛（腦髓空虛）型為主。
목적：연구뇌백질병변적영상학개변급림상특점。방법회고성납입60～85세행MRI검사시뇌백질고신호개변적환자，회고기영상학자료、림상자료，총결귀납뇌백질병변적류형、엄중정도，병사、인지여정서평개결과，진단등。결과뇌백질병변류형이1형、2형위주，분별점총례수적47．45％、31．21％。병변정도균이경도위주：뇌실주위백질경도개변점57．64％，뇌심부백질경도개변점68．79％。병사제시56．69％환고혈압병，28．34％환뇌졸중，29．30％환당뇨병。57．96％환자존재인지공능장애；12．42％환자존재억욱。66례뇌경사，42례아이자해묵병，88례혈관성치태。중의진단위“치태”환자이신정우허（뇌수공허）위주，점58．27％。결론뇌백질병변영상학이경중도개변위주，기발병가능여고혈압、졸중、당뇨병등유관，기병변정도가능여인지공능하강유관，치태환자중의증형이신정우허（뇌수공허）형위주。
Objective To study the imaging changes and clinical features of leukodystrophy.Meth-ods The patients,aged from 60 to 85 years,with high signal changes of alba in MRI examination were in-cluded and their imaging data and clinical data were analyzed retrospectively.The type of leukodystrophy and severity,evaluation results of medical history,cognition and emotion,diagnosis and others were summed up. Results The type 1 and type 2 lukodystrophy are predominated,accounting for 47.45% and 31 .21% re-spectively.Most cases were mild in severity,in which,the mild change in peripheral ventricular white matter accounted for 57.64%,and the white matter of deep brain for 68.79%.The medical history showed that 56.69% of them suffered from hypertension,23.34% of them from stroke and 29.30% from diabetes. 57.96% of patients had cognitive disturbance and 1 2.42% had depression.There were 66 cases of cerebral infarction,42 cases of Alzheimer′s disease and 88 cases of vascular dementia.“Dementia”diagnosed by TCM is predominated as kidney essence deficiency(emptiness of brain marrow)in differentiation,accounting for 58.27%.Conclusion Leukodystrophy is predominated as the mild case in imaging,likely related to hyper-tension,stroke,diabetes,etc.The severity of disease is possibly associated with declining of cognitive func-tion.Dementia in TCM is mainly differentiated as kidney essence deficiency(emptiness of brain marrow).
