CAJ | 학술논문

目的：观察厦门地区102例初诊2型糖尿病患者胰岛素治疗前后中医证素变化特点。方法收集符合纳入标准的102例初诊2型糖尿病患者的临床资料，采用证素辨证方法，观察胰岛素治疗前、治疗后6周及12周时证素的分布及变化特点。结果102例初诊2型糖尿病患者治疗前病位证素以肾、肝证素居多。病性证素中，以热、阴虚、气虚、湿证素为主。治疗6周、12周后，仍以肾、肝证素频数及积分较高；实性证素居前两位的仍为热、湿证素，虚性证素前两位为阴虚、阳虚。结论随着治疗时间的延长，胰岛素可使初诊2型糖尿病患者证素分布发生变化，肾、热、肝、阴虚、湿频数下降，其中气虚频数及积分明显下降，而阳虚频数及证素积分升高。
목적：관찰하문지구102례초진2형당뇨병환자이도소치료전후중의증소변화특점。방법수집부합납입표준적102례초진2형당뇨병환자적림상자료，채용증소변증방법，관찰이도소치료전、치료후6주급12주시증소적분포급변화특점。결과102례초진2형당뇨병환자치료전병위증소이신、간증소거다。병성증소중，이열、음허、기허、습증소위주。치료6주、12주후，잉이신、간증소빈수급적분교고；실성증소거전량위적잉위열、습증소，허성증소전량위위음허、양허。결론수착치료시간적연장，이도소가사초진2형당뇨병환자증소분포발생변화，신、열、간、음허、습빈수하강，기중기허빈수급적분명현하강，이양허빈수급증소적분승고。
Objective To observe the characters of syndrome factor changes in TCM before and af-ter treatment with insulin in 1 02 patients of type 2 diabetes at the first visit in Xiamen region.Methods The clinical data of 1 02 patients of type 2 diabetes at the first visit,in accordance with inclusive standard were collected.The syndrome factors and pattern/syndrome differentiation were adopted to observe the characters of syndrome factor distribution and changes before,in 6 weeks and 1 2 weeks after treatment with insulin sepa-rately.Results Among 1 02 patients of type 2 diabetes,kidney and liver syndromes were predominated;re-garding the nature of disease,heat,yin deficiency,qi deficiency and damp syndromes were predominated be-fore treatment.In 6 weeks and 1 2 weeks after treatment,the frequency and score of kidney and liver syn-dromes were quite high,heat and damp syndromes were at the top two in the category of excess syndrome,and yin deficiency and yang deficiency were at the top two in the category of deficiency.Conclusion With the treatment lasting,insulin changes the distribution of syndrome factor of the patients with type 2 diabetes.The frequencies of kidney,heat,liver,yin deficiency and damp syndromes are reduced,of which,the frequency and score of qi deficiency syndrome are reduced apparently and those of yang deficiency are increased.