CAJ | 학술논문

目的：探讨全结肠系膜切除术（CME）在结肠癌根治术中的应用价值。方法回顾性分析44例接受 CME 手术治疗及40例传统结肠癌根治术的结肠癌患者的临床资料，比较两组患者的近期疗效及安全性。结果CME 组和非 CME 组患者淋巴结清扫数量分别为（23．2±2．3）枚和（16．5±1．8）枚，差异有统计学意义（P ＜0．05）；两组间Ⅰ期和Ⅱ期病例淋巴结清扫数量差异无统计学意义（P ＞0．05），Ⅲ期病例两组淋巴结清扫数量差异有统计学意义（P ＜0．05）。CME 组和非 CME 组中位手术时间分别为195 min 和145 min，差异有统计学意义（P ＜0．05）。两组患者术中出血量、术后恢复时间及术后并发症发生率比较，差异均无统计学意义（P ＞0．05）。结论CME 手术可以达到结肠癌的根治性完整切除，从而达到淋巴结清扫的最大化。术后近期疗效满意，其远期疗效尚待进一步观察。
목적：탐토전결장계막절제술（CME）재결장암근치술중적응용개치。방법회고성분석44례접수 CME 수술치료급40례전통결장암근치술적결장암환자적림상자료，비교량조환자적근기료효급안전성。결과CME 조화비 CME 조환자림파결청소수량분별위（23．2±2．3）매화（16．5±1．8）매，차이유통계학의의（P ＜0．05）；량조간Ⅰ기화Ⅱ기병례림파결청소수량차이무통계학의의（P ＞0．05），Ⅲ기병례량조림파결청소수량차이유통계학의의（P ＜0．05）。CME 조화비 CME 조중위수술시간분별위195 min 화145 min，차이유통계학의의（P ＜0．05）。량조환자술중출혈량、술후회복시간급술후병발증발생솔비교，차이균무통계학의의（P ＞0．05）。결론CME 수술가이체도결장암적근치성완정절제，종이체도림파결청소적최대화。술후근기료효만의，기원기료효상대진일보관찰。
Objective To explore the application values of complete mesocolic excision(CME)in radical operation for colon cancer.Methods The clinical data of 44 cases of CME and 40 cases of tradi-tional radical resection for colon cancer were analyzed retrospectively.Short-term efficacy and safety were compared between the two groups.Results The difference of removed lymph node number between the CME group(23.2 ±2.3)and control group(16.5 ±1.8)was significant(P <0.05).There were no signifi-cant differences in removed lymph node number between the stage I and stage II colon cancer patients(P>0.05).However,for the stage III patients,difference in removed lymph node number between the CME group(25.8 ±3.6)and control group(17.6 ±2.1)was significant(P <0.05).The median operation times for the CME group and control group were 195 min and 145 min respectively(P <0.05).There were no significant differences between two groups in intraoperative blood loss,recovery time and postoperative complications(P >0.05 ).Conclusion The radical resection for colon cancer could be completed by complete mesocolic excision and achieve optimal lymph node harvest.The short-term efficacy is satisfacto-ry,but the long-term efficacy needs further investigation.