风湿病与关节炎
風濕病與關節炎
풍습병여관절염
Rheumatism and Arthritis
2014年
8期
12-14,24
,共4页
骨关节炎,膝%独活寄生汤%膝关节穿刺%玻璃酸钠
骨關節炎,膝%獨活寄生湯%膝關節穿刺%玻璃痠鈉
골관절염,슬%독활기생탕%슬관절천자%파리산납
osteoarthritis,knee%Duhuo Jisheng Decoction%knee joint puncture%sodium hyaluronate
目的：观察独活寄生汤加减联合膝关节穿刺腔内注射玻璃酸钠对老年性膝骨关节炎的近、远期临床疗效。方法：将120例老年性膝骨关节炎患者随机分为治疗组和对照组，每组60例。对照组给予膝关节穿刺腔内注射玻璃酸钠治疗，治疗组在对照组治疗基础上加服独活寄生汤加减治疗，两组均以5周为1个疗程。1个疗程后，观察两组患者的近期疗效，并评价两组患者的膝关节疼痛、压痛、肿胀、晨僵、行走能力。1年后随访两组患者的远期疗效。结果：治疗后，治疗组治愈18例，显效23例，有效16例，无效3例，有效率95.00%；对照组治愈17例，显效14例，有效19例，无效10例，有效率83.33%。两组近期疗效比较，差异无统计学意义（χ2=6.24，P>0.05）。两组膝关节疼痛、压痛、肿胀、晨僵、行走能力分值比均有改善，且治疗组优于对照组（P<0.05）。1年后随访远期疗效，治疗组优于对照组（P<0.05）。结论：膝关节穿刺腔内注射玻璃酸钠对老年性膝骨关节炎近期有显著的效果，但远期效果不能确定；联合口服独活寄生汤加减能明显提高其远期疗效，临床上可根据具体情况加以运用。
目的：觀察獨活寄生湯加減聯閤膝關節穿刺腔內註射玻璃痠鈉對老年性膝骨關節炎的近、遠期臨床療效。方法：將120例老年性膝骨關節炎患者隨機分為治療組和對照組，每組60例。對照組給予膝關節穿刺腔內註射玻璃痠鈉治療，治療組在對照組治療基礎上加服獨活寄生湯加減治療，兩組均以5週為1箇療程。1箇療程後，觀察兩組患者的近期療效，併評價兩組患者的膝關節疼痛、壓痛、腫脹、晨僵、行走能力。1年後隨訪兩組患者的遠期療效。結果：治療後，治療組治愈18例，顯效23例，有效16例，無效3例，有效率95.00%；對照組治愈17例，顯效14例，有效19例，無效10例，有效率83.33%。兩組近期療效比較，差異無統計學意義（χ2=6.24，P>0.05）。兩組膝關節疼痛、壓痛、腫脹、晨僵、行走能力分值比均有改善，且治療組優于對照組（P<0.05）。1年後隨訪遠期療效，治療組優于對照組（P<0.05）。結論：膝關節穿刺腔內註射玻璃痠鈉對老年性膝骨關節炎近期有顯著的效果，但遠期效果不能確定；聯閤口服獨活寄生湯加減能明顯提高其遠期療效，臨床上可根據具體情況加以運用。
목적：관찰독활기생탕가감연합슬관절천자강내주사파리산납대노년성슬골관절염적근、원기림상료효。방법：장120례노년성슬골관절염환자수궤분위치료조화대조조，매조60례。대조조급여슬관절천자강내주사파리산납치료，치료조재대조조치료기출상가복독활기생탕가감치료，량조균이5주위1개료정。1개료정후，관찰량조환자적근기료효，병평개량조환자적슬관절동통、압통、종창、신강、행주능력。1년후수방량조환자적원기료효。결과：치료후，치료조치유18례，현효23례，유효16례，무효3례，유효솔95.00%；대조조치유17례，현효14례，유효19례，무효10례，유효솔83.33%。량조근기료효비교，차이무통계학의의（χ2=6.24，P>0.05）。량조슬관절동통、압통、종창、신강、행주능력분치비균유개선，차치료조우우대조조（P<0.05）。1년후수방원기료효，치료조우우대조조（P<0.05）。결론：슬관절천자강내주사파리산납대노년성슬골관절염근기유현저적효과，단원기효과불능학정；연합구복독활기생탕가감능명현제고기원기료효，림상상가근거구체정황가이운용。
Objective:To observe the clinical curative effects of modiifed Duhuo Jisheng Decoction combined with knee joint cavity injection of medical sodium hyaluronate in the treatment of senile knee osteoarthritis in the near and long terms.Methods:120 cases of senile knee osteoarthritis were randomly and equally divided into a treatment group and a control group.The control group were given the knee joint cavity injection of medical sodium hyaluronate,while the treatment group were given modiifed Duhuo Jisheng Decoction based on the treatment of the control group.Both groups were treated for 5 weeks as a course.After 1 course of treatment,the short-term curative effects in the two groups was observed and the knee joint pain,tenderness,sw elling,morning stiffness,walking ability of the two groups were evaluated.1 year later,follow-up for the long-term effect of the two groups.Results:After treatment,in the treatment group,18 cases were recovery,23 cases were markedly effective,16 cases were effective and 3 cases were invalid,the effective rate being 95.00%.In the control group,17 cases were recovery,14 cases were markedly effective,19 cases were effective and 10 cases were invalid,the effective rate being 83.33%,there being no signiifcant difference between the two groups in the short term (χ2=6.24,P>0.05).The knee joint pain,tenderness,swelling,morning stiffness and walking ability of the two groups were all improved,with the treatment group better than the control group(P<0.05).According to the follow-up for the long-term effect 1 year later,the treatment group was better than the control group(P<0.05). Conclusion:The knee joint cavity injection of sodium hyaluronate had a significant effect on senile knee osteoarthritis in the near term,but that of the long term was uncertain;its combination with modiifed Duhuo Jisheng Decoction could obviously improve the long-term efifcacy,which could be used clinically according to speciifc situations.
