CAJ | 학술논문

目的：研究踝肱指数( ABI)在诊断2型糖尿病患者下肢动脉病变( PAD)中临床意义与影响因素。方法采用多普勒血流探测仪检测2型糖尿病患者足背动脉、胫后动脉与肱动脉血压的比值,以ABI<0.9为切割点分成PAD组和非PAD组,比较两组患者的临床资料并分析其危险因素。结果检出糖尿病下肢血管病变21例(19.8%),其中无临床症状者10例。和非PAD组比较,PAD组患者年龄大,病程长,餐后2 h血糖(2 hPBG)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、糖化血红蛋白(HbA1C)均明显升高,有显著性差异(P<0.05)。结论踝肱指数可用于早期诊断糖尿病下肢血管病变,且无创、价廉、简单,患者易接受。高龄、病程长、高血糖、高TG、LDL-C是引起下肢血管病变的危险因素。
목적：연구과굉지수( ABI)재진단2형당뇨병환자하지동맥병변( PAD)중림상의의여영향인소。방법채용다보륵혈류탐측의검측2형당뇨병환자족배동맥、경후동맥여굉동맥혈압적비치,이ABI<0.9위절할점분성PAD조화비PAD조,비교량조환자적림상자료병분석기위험인소。결과검출당뇨병하지혈관병변21례(19.8%),기중무림상증상자10례。화비PAD조비교,PAD조환자년령대,병정장,찬후2 h혈당(2 hPBG)、감유삼지(TG)、저밀도지단백(LDL-C)、당화혈홍단백(HbA1C)균명현승고,유현저성차이(P<0.05)。결론과굉지수가용우조기진단당뇨병하지혈관병변,차무창、개렴、간단,환자역접수。고령、병정장、고혈당、고TG、LDL-C시인기하지혈관병변적위험인소。
Objective To investigate ankle-brachial index( ABI) in the diagnosis of peripheral artery disease( PAD) and its risk factors in the patients with type 2 diabetes. Methods ABI was examined in the 106 patients with type 2 diabetes,who were assigned into the group with low ABI (ABI<0. 9) and the group with normal ABI(ABI≥0. 9). Clinical data and risk factors were analyzed. ResultTwenty-one patients(19. 8%)with abnormal ABI(ABI<0. 9)were detected,10 of which had not been found any symptoms. Group with low ABI showed older age,longer diabetes duration,higher 2 h post-meal glucose levels and higher levels of triglycerides,LDL-C( P<0. 05). Conclusions Detection of ABI could adopted in the early diagnosis of PAD in diabetic patients,which can be accepted easily because of cheap and non-invasive character. Patients with old age,long duration,hyperglycemia,high levels of triglycerides have more and severer macrovascular risk factors.