CAJ | 학술논문

探讨黄秋葵果实粉（OFP）对D-半乳糖致衰老模型小鼠抗氧化能力的影响。以昆明种小鼠为研究对象，颈背部皮下注射D-半乳糖造模。正常对照组、模型对照组饲喂基础饲料，实验组小鼠饲喂含受试物低、中、高剂量（32.00、64.00、128.00 g/kg）饲料，实验期56 d，测定血清和肝组织匀浆中超氧化物岐化酶（SOD）、谷胱苷肽过氧化物酶（GSH-Px）、过氧化氢酶（CAT）的活性及丙二醛（MDA）的含量。D-半乳糖致衰小鼠SOD活性、GSH-Px活性和CAT活性均明显下降，MDA含量明显上升，与正常小鼠比较差异显著；饲喂不同剂量的黄秋葵果实粉后均能提高小鼠血清、肝脏组织中的SOD、GSH-Px和CAT活性，同时降低血清、肝脏组织中MDA含量。适量摄入黄秋葵果实粉能显著提高衰老小鼠的抗氧化能力，具有一定延缓衰老的作用。
탐토황추규과실분（OFP）대D-반유당치쇠로모형소서항양화능력적영향。이곤명충소서위연구대상，경배부피하주사D-반유당조모。정상대조조、모형대조조사위기출사료，실험조소서사위함수시물저、중、고제량（32.00、64.00、128.00 g/kg）사료，실험기56 d，측정혈청화간조직균장중초양화물기화매（SOD）、곡광감태과양화물매（GSH-Px）、과양화경매（CAT）적활성급병이철（MDA）적함량。D-반유당치쇠소서SOD활성、GSH-Px활성화CAT활성균명현하강，MDA함량명현상승，여정상소서비교차이현저；사위불동제량적황추규과실분후균능제고소서혈청、간장조직중적SOD、GSH-Px화CAT활성，동시강저혈청、간장조직중MDA함량。괄량섭입황추규과실분능현저제고쇠로소서적항양화능력，구유일정연완쇠로적작용。
To investigate the effects of Okra fruit powder (OFP) on antioxidant abilities in aged mice induced by D-galactose. The subacute aged model mice were made by neck back subcutaneous injection of D-galactose continually. The mice were given different doses of Okra fruit powder 32.00,64.00 g/kg and 128.00 g/kg fed by diet for 56 d respectively.The content of malondialdehyde (MDA)and activity of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) and catalase (CAT) in the serum and liver of the mice were tested. The SOD, GSH-Px and CAT activities in aged model group were significantly decreased and MDA significantly increased compared with normal mice;OFP in different doses evidently increased the SOD, GSH-Px and CAT activities and reduced the MDA level in serum and liver in mice. OFP can obviously increase the antioxidant ability of mice.