中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
23期
22-23
,共2页
氯吡格雷%阿司匹林%急性冠脉综合征
氯吡格雷%阿司匹林%急性冠脈綜閤徵
록필격뢰%아사필림%급성관맥종합정
Clopidogrel%Aspirin%Acute coronary syndrome
目的：探讨氯吡格雷治疗急性冠脉综合征的临床疗效。方法：选取2011年1月-2013年12月在笔者所在医院收治的120例急性冠脉综合征患者，采用随机数字表法将其分为试验组与对照组，各60例。对照组给予阿司匹林治疗，试验组给予阿司匹林联合氯吡格雷治疗，比较两组患者的临床治疗效果和心血管不良反应发生率。结果：试验组临床治疗的总有效率为93.3%，明显高于对照组的71.7%，差异有统计学意义(P<0.05)。治疗后，两组肌钙蛋白水平均下降，但试验组患者下降更为明显，与对照组比较差异有统计学意义(P<0.05)。试验组患者心血管不良反应的发生率6.67%低于对照组的20.0%，差异有统计学意义(P<0.05)。结论：氯吡格雷能够显著改善急性冠脉综合征患者的临床症状，有效降低患者的肌钙蛋白水平，临床疗效显著，同时可有效降低心血管不良反应的发生，安全、有效，是治疗急性冠脉综合征的有效药物。
目的：探討氯吡格雷治療急性冠脈綜閤徵的臨床療效。方法：選取2011年1月-2013年12月在筆者所在醫院收治的120例急性冠脈綜閤徵患者，採用隨機數字錶法將其分為試驗組與對照組，各60例。對照組給予阿司匹林治療，試驗組給予阿司匹林聯閤氯吡格雷治療，比較兩組患者的臨床治療效果和心血管不良反應髮生率。結果：試驗組臨床治療的總有效率為93.3%，明顯高于對照組的71.7%，差異有統計學意義(P<0.05)。治療後，兩組肌鈣蛋白水平均下降，但試驗組患者下降更為明顯，與對照組比較差異有統計學意義(P<0.05)。試驗組患者心血管不良反應的髮生率6.67%低于對照組的20.0%，差異有統計學意義(P<0.05)。結論：氯吡格雷能夠顯著改善急性冠脈綜閤徵患者的臨床癥狀，有效降低患者的肌鈣蛋白水平，臨床療效顯著，同時可有效降低心血管不良反應的髮生，安全、有效，是治療急性冠脈綜閤徵的有效藥物。
목적：탐토록필격뢰치료급성관맥종합정적림상료효。방법：선취2011년1월-2013년12월재필자소재의원수치적120례급성관맥종합정환자，채용수궤수자표법장기분위시험조여대조조，각60례。대조조급여아사필림치료，시험조급여아사필림연합록필격뢰치료，비교량조환자적림상치료효과화심혈관불량반응발생솔。결과：시험조림상치료적총유효솔위93.3%，명현고우대조조적71.7%，차이유통계학의의(P<0.05)。치료후，량조기개단백수평균하강，단시험조환자하강경위명현，여대조조비교차이유통계학의의(P<0.05)。시험조환자심혈관불량반응적발생솔6.67%저우대조조적20.0%，차이유통계학의의(P<0.05)。결론：록필격뢰능구현저개선급성관맥종합정환자적림상증상，유효강저환자적기개단백수평，림상료효현저，동시가유효강저심혈관불량반응적발생，안전、유효，시치료급성관맥종합정적유효약물。
Objective:To evaluate the clinical efficacy of clopidogrel in acute coronary syndrome. Method:120 cases of patients with acute coronary syndrome were treated from January 2011 to December 2013 in author’s hospital,were randomly divided into experimental group and control group,60 cases in each.The control group was given aspirin therapy,the experimental group was given aspirin plus clopidogrel treatment,the incidence of the two groups were compared the clinical efficacy and adverse cardiovascular response.Result:Clinical treatment in experimental group,the total effective rate was 93.3%, significantly higher than 71.7% in the control group,the difference was statistically significant(P<0.05).After treatment,troponin levels in two groups were decreased,but the experimental group decreased more significantly,there was statistically significant difference compared with the control group(P<0.05).The incidence was 6.67%lower than that of the control group of 20%patients with cardiovascular adverse reactions to the test group,the difference was statistically significant(P<0.05).Conclusion:Clopidogrel can significantly improve clinical symptoms in patients with acute coronary syndrome,effectively reduce the patient’s troponin levels,a significant clinical effect,and can effectively reduce the incidence of cardiovascular adverse reactions,safe,effective,is an effective drug for treatment of acute coronary syndrome.
