CAJ | 학술논문

目的：探究胃远端大部切除术并行毕Ⅱ式吻合术对胃癌合并2型糖尿病患者的血糖代谢的影响。方法：2007年2月-2014年2月收治胃癌合并2型糖尿病患者105例，随机分为甲(行毕Ⅰ式吻合术)、乙(行毕Ⅱ式吻合术)、丙(行Roux-en-Y吻合术)3组，比较3组术前、术后1周、术后1个月、术后6个月的空腹血糖、餐后2小时血糖、糖化血红蛋白和糖尿病的治愈率、改善率、无效率。结果：与手术前相比，甲组、乙组、丙组术后1周、术后1个月、术后6个月的空腹血糖、餐后2小时血糖、糖化血红蛋白均降低，差异有统计学意义(P＜0.05)；与甲组相比，乙组和丙组术后1个月、术后6个月的空腹血糖、餐后2小时血糖、糖化血红蛋白较低，差异有统计学意义(P＜0.05)。与甲组相比，乙组和丙组糖尿病治愈例数较高，而无效例数较少，差异有统计学意义(P＜0.05)。结论：胃远端大部切除术并行毕Ⅱ式吻合术对胃癌合并2型糖尿病患者具有良好的控制血糖的作用，能提高患者糖尿病的治愈率。
목적：탐구위원단대부절제술병행필Ⅱ식문합술대위암합병2형당뇨병환자적혈당대사적영향。방법：2007년2월-2014년2월수치위암합병2형당뇨병환자105례，수궤분위갑(행필Ⅰ식문합술)、을(행필Ⅱ식문합술)、병(행Roux-en-Y문합술)3조，비교3조술전、술후1주、술후1개월、술후6개월적공복혈당、찬후2소시혈당、당화혈홍단백화당뇨병적치유솔、개선솔、무효솔。결과：여수술전상비，갑조、을조、병조술후1주、술후1개월、술후6개월적공복혈당、찬후2소시혈당、당화혈홍단백균강저，차이유통계학의의(P＜0.05)；여갑조상비，을조화병조술후1개월、술후6개월적공복혈당、찬후2소시혈당、당화혈홍단백교저，차이유통계학의의(P＜0.05)。여갑조상비，을조화병조당뇨병치유례수교고，이무효례수교소，차이유통계학의의(P＜0.05)。결론：위원단대부절제술병행필Ⅱ식문합술대위암합병2형당뇨병환자구유량호적공제혈당적작용，능제고환자당뇨병적치유솔。
Objective:To investigate the influence of distal gastrectomy parallel Bi Ⅱ type on glucose metabolism in patients with type 2 diabetes mellitus combined gastric cancer.Methods:105 cases with type 2 diabetes combined gastric cancer were selected from February 2007 to February 2014.They were randomly divided into the A group(for Billroth anastomosis),B group(for Bi Ⅱanastomosis),C group(Roux-en-Y anastomosis).Compare the fasting blood glucose,postprandial 2 hour blood glucose,glycosylated hemoglobin and diabetes cure rate,improvement rate,invalid rate of patients in three groups before operation,1 week,1 months and 6 months after the surgery.Results:Compared with before operation,fasting blood glucose,postprandial 2 hour blood glucose and glycosylated hemoglobin of group A,group B,group C in 1 weeks,1 months and 6 months after operation were decreased,and the difference was statistically significant(P<0.05).Compared with group A,fasting blood glucose,postprandial 2 hour blood glucose, glycosylated hemoglobin of group B and group C in 1 months and 6 months after operation were low,and the difference was statistically significant(P<0.05).Compared with group A,the number of diabetes cure in group B and group C were higher,and the number of invalid were less.The difference were statistically significant(P<0.05).Conclusion:Distal gastrectomy parallel Bi Ⅱtype can better control glycaemic in patients with type 2 diabetic combined gastric cancer.It also can improve the cure rate in patients with diabetes mellitus.