CAJ | 학술논문

目的：探讨术前预防性使用抗生素在Ⅰ类切口手术患者中的应用价值。方法选取100例Ⅰ类切口手术的患者随机分为观察组和对照组，对照组术前不使用抗生素，观察组术前预防性使用抗生素，比较2组的体温、相关实验数据以及术后切口情况。结果观察组术后1 d、2 d、3 d 的体温与对照组比较差异无统计学意义（P ＞0．05）。观察组术后的外周白细胞计数、切口的甲级愈合率、感染率与对照组比较差异无统计学意义（P ＞0．05）。观察组术后的中性粒细胞分类少于对照组，差异有统计学意义（P ＜0．05），但均在正常范围之内。结论术前预防性使用抗生素并不能降低Ⅰ类手术切口患者感染的发生率，不主张预防性使用抗生素。
목적：탐토술전예방성사용항생소재Ⅰ류절구수술환자중적응용개치。방법선취100례Ⅰ류절구수술적환자수궤분위관찰조화대조조，대조조술전불사용항생소，관찰조술전예방성사용항생소，비교2조적체온、상관실험수거이급술후절구정황。결과관찰조술후1 d、2 d、3 d 적체온여대조조비교차이무통계학의의（P ＞0．05）。관찰조술후적외주백세포계수、절구적갑급유합솔、감염솔여대조조비교차이무통계학의의（P ＞0．05）。관찰조술후적중성립세포분류소우대조조，차이유통계학의의（P ＜0．05），단균재정상범위지내。결론술전예방성사용항생소병불능강저Ⅰ류수술절구환자감염적발생솔，불주장예방성사용항생소。
Objective To explore the application value of antibiotic prophylaxis in patients with type I incision operation.Methods 100 patients with type I incision operation were random-ly divided into the observation group and the control group,the control group didn’t use antibiotics before operation while the observation group was given antibiotic prophylaxis,body temperature, experimental data and postoperative incision were compared between the two groups.Results The difference was not statistical significant in the temperature of the 1st day,2nd day and 3rd day af-ter operation in the observation group compared with the control group (P >0.05).The difference was not statistical significant in peripheral white blood cell count,infection rate and the class-A healing rate in the observation group compared with the control group (P >0.05).The difference was statistically significant since neutrophils in the observation group was less than that in the con-trol group (P <0.05),but they were all in the normal range.Conclusion Antibiotic prophylaxis couldn’t reduce the occurrence rate of incision infection for patients with type I incision operation, so the use of prophylactic antibiotics is not advocated.