CAJ | 학술논문

目的：探讨超声心动图测定在胎儿先天性心脏病产前超声诊断中的临床效果。方法采用 LOGIQ 7超声诊断仪检查528例先心病高危胎儿，在心脏超声四腔观基础上测定胎儿心脏轴，并从多切面观察胎儿心内结构，以确定胎儿有无先心病。结果在528例先心病高危胎儿中，单纯四腔观检测有先天性心脏病胎儿29例，正常胎儿499例；而心脏超声四腔观加心脏轴测定共检测有先天性心脏病胎儿43例，正常胎儿485例，差异有统计学意义（P ＜0．01）。经过引产儿尸体解剖、新生儿超声检查以及随访手术结果确诊后，确诊胎儿先天性心脏病者46例，单纯四腔观检测胎儿先心病的敏感性为63．04％（29/46），应用心脏超声四腔观加心脏轴测定检测胎儿先心病的敏感性为93．48％（43/46），差异有统计学意义（P ＜0．05）。结论应用超声心脏轴测定在筛选胎儿先天性心脏病中可操作性强，且具有十分重要的临床意义。
목적：탐토초성심동도측정재태인선천성심장병산전초성진단중적림상효과。방법채용 LOGIQ 7초성진단의검사528례선심병고위태인，재심장초성사강관기출상측정태인심장축，병종다절면관찰태인심내결구，이학정태인유무선심병。결과재528례선심병고위태인중，단순사강관검측유선천성심장병태인29례，정상태인499례；이심장초성사강관가심장축측정공검측유선천성심장병태인43례，정상태인485례，차이유통계학의의（P ＜0．01）。경과인산인시체해부、신생인초성검사이급수방수술결과학진후，학진태인선천성심장병자46례，단순사강관검측태인선심병적민감성위63．04％（29/46），응용심장초성사강관가심장축측정검측태인선심병적민감성위93．48％（43/46），차이유통계학의의（P ＜0．05）。결론응용초성심장축측정재사선태인선천성심장병중가조작성강，차구유십분중요적림상의의。
Objective To investigate the clinical significance of cardiac axis determined by echocardiography in the diagnosis of fetal congenital heart disease (CHD).Methods 528 high risk fetuses for CHD were examined by echocardiography.Cardiac axis was measured on four chamber view and fetal cardic anatomical structure was examined in multiple views to determine CHD.Re-sults 29 cases of fetal congenital heart disease and 499 cases of normal fetus were detected by four chamber view in 528 cases of congenital heart disease risk in the fetus pure.However,43 cases of fetal congenital heart disease and 485 cases of normal fetus were detected by combination of four Chamber view and cardiac axis determination in 528 cases of congenital heart disease risk in the fetus pure(P <0.01).Finally,46 cases of fetal congenital heart diseas were diagnosed through perinatal autopsy,newborn ultrasound examination or the results after diagnosis.Sensitivity of CHD diag-nosed by four chamber view alone was 63.04%.However,it was elevated to 93.48% by combina-tion of four Chamber view and cardiac axis determination (P <0.05).Conclusion Cardiac axis plays a key role in fetal echocardiographic screening for CHD.