CAJ | 학술논문

目的：探讨丹参酮ⅡA 磺酸钠注射液配合西药常规方法治疗肺源性心脏病的临床效果。方法将56例应用丹参酮液配合西药治疗肺源性心脏病病例作为治疗组，与同期住院单用西药治疗同类病例30例作为对照组，探讨临床效果、临床症状改善情况、血气分析指标改善情况。结果2组治疗总有效率无显著差异（P ＞0．05）；2组治疗后咳嗽、喘憋、水肿、紫绀、心悸、痰多等症状均有改善，治疗组咳嗽的好转率显著高于对照组（P ＜0．05）；2组治疗后肺活量、血氧浓度均显著增加（P ＜0．01），血二氧化碳浓度均显著下降（P ＜0．01）。治疗组治疗后肺活量、血氧浓度显著高于对照组（P ＜0．05），血二氧化碳浓度显著低于对照组（P ＜0．01）。结论在西医治疗基础上加用丹参酮ⅡA 磺酸钠能提高对肺心病患者的临床疗效，明显改善临床症状，增强肺功能，疗效优于西医常规治疗。
목적：탐토단삼동ⅡA 광산납주사액배합서약상규방법치료폐원성심장병적림상효과。방법장56례응용단삼동액배합서약치료폐원성심장병병례작위치료조，여동기주원단용서약치료동류병례30례작위대조조，탐토림상효과、림상증상개선정황、혈기분석지표개선정황。결과2조치료총유효솔무현저차이（P ＞0．05）；2조치료후해수、천별、수종、자감、심계、담다등증상균유개선，치료조해수적호전솔현저고우대조조（P ＜0．05）；2조치료후폐활량、혈양농도균현저증가（P ＜0．01），혈이양화탄농도균현저하강（P ＜0．01）。치료조치료후폐활량、혈양농도현저고우대조조（P ＜0．05），혈이양화탄농도현저저우대조조（P ＜0．01）。결론재서의치료기출상가용단삼동ⅡA 광산납능제고대폐심병환자적림상료효，명현개선림상증상，증강폐공능，료효우우서의상규치료。
Objective To explore the clinical efficacy of tanshinone ⅡA sodium injection combined with routine therapies of western medicine on patients with pulmonary heart disease-in-duced heart failure (PHDHF).Methods Fifty-six patients with PHDHF treated with tanshinone injection combined with routine therapies of western medicine were selected as treatment group while 30 patients with same disease given single routine western medicine served as control group. Clinical efficacy and improvement of effect and blood gas analysis indications were explored.Results There was no significant difference in clinical efficacy between two groups.Cough,asthma, swelling,cyanosis,palpitation and abundant phlegm,etc,were improved obviously after treatment in both group,in which the improvement rate of cough was higher in treatment group than in con-trol group (P <0.05).Lung capacity and blood oxygen concentration increased apparently in both groups (P <0.01)and were evidently higher in treatment group (P <0.05),whereas blood carbon dioxide concentration decreased markedly (P <0.01)and was significantly lower in treatment group than in control group (P <0.01).Conclusion Integrated Chinese and western medicine are more effective in treating PHDHF than routine therapies of single western medicine in evidently promot-ing the clinical efficacy and pulmonary function.