CAJ | 학술논문

目的：进行男性初发2型糖尿病患者血游离脂肪酸、尿酸、睾酮与 C 肽的相关性分析。方法选取本院门诊及住院的初发2型糖尿病患者41例，检测相关指标与 C 肽进行的相关性分析。结果血清 C 肽与年龄、BMI、血尿酸水平、空腹胰岛素、游离脂肪酸、胰岛素抵抗（HOMA-IR）、胰岛素分泌指数（HOMA-B）呈显著正相关，与糖化血红蛋白呈负相关，与睾酮无显著相关性，且多元线性回归分析显示尿酸是 C 肽的独立影响因素。结论男性初发2型糖尿病患者年龄、肥胖、尿酸、游离脂肪酸、糖化血红蛋白与 C 肽密切相关，高尿酸血症是 C 肽的独立影响因素，而睾酮未示与 C 肽的相关性。
목적：진행남성초발2형당뇨병환자혈유리지방산、뇨산、고동여 C 태적상관성분석。방법선취본원문진급주원적초발2형당뇨병환자41례，검측상관지표여 C 태진행적상관성분석。결과혈청 C 태여년령、BMI、혈뇨산수평、공복이도소、유리지방산、이도소저항（HOMA-IR）、이도소분비지수（HOMA-B）정현저정상관，여당화혈홍단백정부상관，여고동무현저상관성，차다원선성회귀분석현시뇨산시 C 태적독립영향인소。결론남성초발2형당뇨병환자년령、비반、뇨산、유리지방산、당화혈홍단백여 C 태밀절상관，고뇨산혈증시 C 태적독립영향인소，이고동미시여 C 태적상관성。
Objective To conduct a relevance analysis of blood free fatty acid (FFA),uric acid (UA)and testosterone (TTE)with C peptide in male patients with incipient type 2 diabetes mellitus (T2DM).Methods A total of 41 patients with incipient T2DM in outpatient or hospital-ized in our hospital were selected to detect the relevance between relevant indexes and C peptide. Results Serum C peptide was in positive relation with ages,body mass index (BMI),UA level, fasting insulin,FFA,homeostasis model assessment of Insulin Resistance (HOMA-IR)and home-ostasis model assessment-B (HOMA-B)and in reverse connection with glycated hemoglobin,but in no relationship with TTE.Additionally,the multiple linear regression analysis showed that UA was an independent risk factor for C peptide.Conclusion Serum C peptide is in close association with ages,obesity,UA,FFA and glycated hemoglobin and its independent risk factor is Hyperuricemia, which has no correlation with TTE in male patients with incipient T2DM.