CAJ | 학술논문

目的：探讨盐酸埃克替尼靶向治疗期间进行手术干预治疗非小细胞肺癌（NSCLC）的可行性。方法回顾性分析经盐酸埃克替尼靶向治疗后在不同时机采取手术干预的6例 NSCLC 患者的临床资料。结果6例患者经盐酸埃克替尼靶向治疗后，均施行手术干预治疗，其中行左全肺切除1例，肺叶切除3例，局部切除2例。手术过程顺利，术后给予化疗2例，继续靶向治疗3例，观察1例。结论盐酸埃克替尼靶向治疗期间给予适当、适时、主动的手术干预是可行的。
목적：탐토염산애극체니파향치료기간진행수술간예치료비소세포폐암（NSCLC）적가행성。방법회고성분석경염산애극체니파향치료후재불동시궤채취수술간예적6례 NSCLC 환자적림상자료。결과6례환자경염산애극체니파향치료후，균시행수술간예치료，기중행좌전폐절제1례，폐협절제3례，국부절제2례。수술과정순리，술후급여화료2례，계속파향치료3례，관찰1례。결론염산애극체니파향치료기간급여괄당、괄시、주동적수술간예시가행적。
Objective To investigate the feasibility of surgical intervention on treatment of patients with non-small cell lung cancer (NSCLC)in icotinib hydrochloride targeted treatment. Methods Clinical materials of 6 patients given surgical intervention after icotinib hydrochloride tar-geted therapy were retrospectively analyzed.Results Among 6 patients,1 patient had left total pneumonectomy,3 patients had pulmonary lobectomy,2 patients had local excision.After opera-tion,number of patients with chemotherapy,targeted therapy and observation only was 2,3 and 1 case respectively.Conclusion Well-designed and active surgical intervention may be feasible for patient during icotinib hydrochloride targeted therapy.