CAJ | 학술논문

目的：观察左卡尼汀佐治小儿轮状病毒肠炎合并心肌损害的疗效。方法将61例轮状病毒肠炎合并心肌损害的患儿随机分为治疗组（31例）和对照组（30例），2组患儿均给予常规治疗。在此基础上，对照组加用维生素 C 及能量合剂营养心肌治疗；治疗组加用左卡尼汀，疗程均为14 d。观察治疗前后患儿心肌酶谱、心电图的改变情况以及治疗有效率。结果治疗后2组心肌酶均较治疗前下降，但治疗组下降较对照组更明显（P ＜0．05）；治疗组心电图恢复正常率（91．6％）优于对照组（83．3％），但2组间差异无统计学意义（P ＞0．05）。治疗组与对照组总有效率分别为96．8％和73．3％，差异有统计学意义（P＜0．05）。结论左卡尼汀治疗小儿轮状病毒肠炎合并心肌损害具有良好的临床疗效，值得推广。
목적：관찰좌잡니정좌치소인륜상병독장염합병심기손해적료효。방법장61례륜상병독장염합병심기손해적환인수궤분위치료조（31례）화대조조（30례），2조환인균급여상규치료。재차기출상，대조조가용유생소 C 급능량합제영양심기치료；치료조가용좌잡니정，료정균위14 d。관찰치료전후환인심기매보、심전도적개변정황이급치료유효솔。결과치료후2조심기매균교치료전하강，단치료조하강교대조조경명현（P ＜0．05）；치료조심전도회복정상솔（91．6％）우우대조조（83．3％），단2조간차이무통계학의의（P ＞0．05）。치료조여대조조총유효솔분별위96．8％화73．3％，차이유통계학의의（P＜0．05）。결론좌잡니정치료소인륜상병독장염합병심기손해구유량호적림상료효，치득추엄。
Objective To explore the clinical effect of l-carnitine on pedeatric rotavirus en-teritis combined with myocardial damage.Methods 61 patients with pedeatric rotavirus enteritis combined with myocardial damage were randomly divided into treatment group (31 cases)and con-trol group (30 cases).Both groups were given routine treatment.Based on this,control group was treated with vitamin C and energy mixture while treatment group was treated with L-carnitine oral solution,14 days,respectively.Cardiac enzymes,ECG and treatment efficiency were observed.Re-sults Myocardial enzyme levels in both groups were lower than those before treatment,and the treatment group was lower than control group (P <0.05),and the ECG recovery rates in treatment group (91.6%)was higher than that in control group (83.3%)(P >0.05).The total effective rate of the treatment group(96.8%)was obviously higher than that of the control group (73.3%) (P <0.05).Conclusion L-carnitine in treatment of infant rotavirus enteritis combined with the myocardial damage is effective,which is worthy of clinical popularization.