实用临床医药杂志
實用臨床醫藥雜誌
실용림상의약잡지
JOURNAL OF JIANGSU CLINICAL MEDICINE
2014年
16期
112-114
,共3页
多索茶碱%AECOPD%APACHEⅡ评分系统%机械通气
多索茶堿%AECOPD%APACHEⅡ評分繫統%機械通氣
다색다감%AECOPD%APACHEⅡ평분계통%궤계통기
doxofylline%AECOPD%APACHEⅡscore%mechanical ventilation
目的：探讨 APACHEⅡ评分不同的慢性阻塞性肺疾病急性加重期（AECOPD）患者应用多索茶碱不同给药方式对机械通气撤机时间的影响。方法选取本院 ICU 病房 AECOPD 病人经有创机械通气治疗并成功脱机患者45例，其中 A-PACHEⅡ＜20使用多索茶碱持续泵入组13例和静点组11例，APACHEⅡ≥20多索茶碱持续泵入组11例和静点组10例，观察不同 APACHEⅡ评分病人多索茶碱持续泵入组与多索茶碱静点组对机械通气撤机时间的影响。结果多索茶碱持续泵入组在 APACHEⅡ＜20的撤机时间早于多索茶碱静点组，差异有统计学意义（P ＜0．05）；与 APACHEⅡ≥20比较，多索茶碱持续泵入组与多索茶碱静点组差异无统计学意义（P ＞0．05）。结论 AECOPD 机械通气撤机时间受 APACHEⅡ评分影响，多索茶碱持续泵入治疗能缩短 APACHEⅡ＜20机械通气时间，提高脱机率。
目的：探討 APACHEⅡ評分不同的慢性阻塞性肺疾病急性加重期（AECOPD）患者應用多索茶堿不同給藥方式對機械通氣撤機時間的影響。方法選取本院 ICU 病房 AECOPD 病人經有創機械通氣治療併成功脫機患者45例，其中 A-PACHEⅡ＜20使用多索茶堿持續泵入組13例和靜點組11例，APACHEⅡ≥20多索茶堿持續泵入組11例和靜點組10例，觀察不同 APACHEⅡ評分病人多索茶堿持續泵入組與多索茶堿靜點組對機械通氣撤機時間的影響。結果多索茶堿持續泵入組在 APACHEⅡ＜20的撤機時間早于多索茶堿靜點組，差異有統計學意義（P ＜0．05）；與 APACHEⅡ≥20比較，多索茶堿持續泵入組與多索茶堿靜點組差異無統計學意義（P ＞0．05）。結論 AECOPD 機械通氣撤機時間受 APACHEⅡ評分影響，多索茶堿持續泵入治療能縮短 APACHEⅡ＜20機械通氣時間，提高脫機率。
목적：탐토 APACHEⅡ평분불동적만성조새성폐질병급성가중기（AECOPD）환자응용다색다감불동급약방식대궤계통기철궤시간적영향。방법선취본원 ICU 병방 AECOPD 병인경유창궤계통기치료병성공탈궤환자45례，기중 A-PACHEⅡ＜20사용다색다감지속빙입조13례화정점조11례，APACHEⅡ≥20다색다감지속빙입조11례화정점조10례，관찰불동 APACHEⅡ평분병인다색다감지속빙입조여다색다감정점조대궤계통기철궤시간적영향。결과다색다감지속빙입조재 APACHEⅡ＜20적철궤시간조우다색다감정점조，차이유통계학의의（P ＜0．05）；여 APACHEⅡ≥20비교，다색다감지속빙입조여다색다감정점조차이무통계학의의（P ＞0．05）。결론 AECOPD 궤계통기철궤시간수 APACHEⅡ평분영향，다색다감지속빙입치료능축단 APACHEⅡ＜20궤계통기시간，제고탈궤솔。
Objective To study effects of doxophylline of different administration methods on weaning time of acute exacerbation of chronic obstructive pulmonary diseases(AECOPD)of A-PACHEⅡ score.Methods 45 patients with AECOPD treated with mechanical ventilation and successful ventilator weaning were selected.In APACHEⅡ<20 patients,13 cases with doxo-fylline by continuous pump were in continuous pump group and 11cases in intravenous drip group;In APACHEⅡ≥20 patients,there were doxofylline by continuous pump with 11 cases and Doxo-fylline by intravenous drip with 10 cases,the effect of ventilator weaning time in different A-PACHEⅡscore between doxofylline by continuous pump and intravenous drip were observed.Re-sults The ventilator weaning time of doxofylline by continuous pump and intravenous drip were compared in APACHEⅡ<20,which was statistically significant difference (P <0.05).but there was no significant difference in APACHEⅡ≥20(P >0.05).Conclusion Ventilator weaning time of AECOPD is influenced by APACHEⅡ score.Continuous pump into doxofylline can obvi-ously relieve mechanical ventilation time in APACHEⅡ<20 and improve the rate of weaning time.
