中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2014年
17期
2635-2636,2637
,共3页
脑缺血%C反应蛋白质%预后
腦缺血%C反應蛋白質%預後
뇌결혈%C반응단백질%예후
Brain ischemia%C-reactive protein%prognosis
目的：探讨血清CRP水平与缺血性脑梗死预后的关系。方法对73例缺血性脑梗死患者（观察组）及同期健康志愿者41例（对照组）进行血清CRP检测，对比两组CRP的变化情况。观察组患者随访观察1年。结果观察组CRP（15．16±7．01）mg/L，显著高于对照组的（4．51±1．36）mg/L，差异有统计学意义（t＝7．153，P＜0．05）；观察组中大、中梗死灶面积患者CRP分别为（18．13±10．07）mg/L、（15．21±7.34）mg/L，明显高于小梗死灶面积患者的（9．95±6．14）mg/L，差异均有统计学意义（t＝7．316、6．541，均P＜0．05）；观察组重、中型患者CRP分别为（19．13±12．24） mg/L、（16．32±8．16） mg/L，显著高于轻型患者的（9.93±5．41）mg/L，差异均有统计学意义（t＝8．153、7．692，均P＜0．05）；随访过程中，复发脑梗死及死亡患者血清CRP分别为（16．12±8．67）mg/L、（19．17±11．36）mg/L，明显高于预后较好患者的（11．32±8.43）mg/L，差异均有统计学意义（t＝7．583、8．751，均P＜0．05）。结论临床上可以将血清CRP水平作为预测脑梗死预后的指标之一。
目的：探討血清CRP水平與缺血性腦梗死預後的關繫。方法對73例缺血性腦梗死患者（觀察組）及同期健康誌願者41例（對照組）進行血清CRP檢測，對比兩組CRP的變化情況。觀察組患者隨訪觀察1年。結果觀察組CRP（15．16±7．01）mg/L，顯著高于對照組的（4．51±1．36）mg/L，差異有統計學意義（t＝7．153，P＜0．05）；觀察組中大、中梗死竈麵積患者CRP分彆為（18．13±10．07）mg/L、（15．21±7.34）mg/L，明顯高于小梗死竈麵積患者的（9．95±6．14）mg/L，差異均有統計學意義（t＝7．316、6．541，均P＜0．05）；觀察組重、中型患者CRP分彆為（19．13±12．24） mg/L、（16．32±8．16） mg/L，顯著高于輕型患者的（9.93±5．41）mg/L，差異均有統計學意義（t＝8．153、7．692，均P＜0．05）；隨訪過程中，複髮腦梗死及死亡患者血清CRP分彆為（16．12±8．67）mg/L、（19．17±11．36）mg/L，明顯高于預後較好患者的（11．32±8.43）mg/L，差異均有統計學意義（t＝7．583、8．751，均P＜0．05）。結論臨床上可以將血清CRP水平作為預測腦梗死預後的指標之一。
목적：탐토혈청CRP수평여결혈성뇌경사예후적관계。방법대73례결혈성뇌경사환자（관찰조）급동기건강지원자41례（대조조）진행혈청CRP검측，대비량조CRP적변화정황。관찰조환자수방관찰1년。결과관찰조CRP（15．16±7．01）mg/L，현저고우대조조적（4．51±1．36）mg/L，차이유통계학의의（t＝7．153，P＜0．05）；관찰조중대、중경사조면적환자CRP분별위（18．13±10．07）mg/L、（15．21±7.34）mg/L，명현고우소경사조면적환자적（9．95±6．14）mg/L，차이균유통계학의의（t＝7．316、6．541，균P＜0．05）；관찰조중、중형환자CRP분별위（19．13±12．24） mg/L、（16．32±8．16） mg/L，현저고우경형환자적（9.93±5．41）mg/L，차이균유통계학의의（t＝8．153、7．692，균P＜0．05）；수방과정중，복발뇌경사급사망환자혈청CRP분별위（16．12±8．67）mg/L、（19．17±11．36）mg/L，명현고우예후교호환자적（11．32±8.43）mg/L，차이균유통계학의의（t＝7．583、8．751，균P＜0．05）。결론림상상가이장혈청CRP수평작위예측뇌경사예후적지표지일。
Objective To investigate the relationship between changes in C-reactive protein and prognosis of ischemic stroke.Methods C-reactive protein were detected in 73 cases with ischemic stroke serum and selected be as a study group ,while collecting ,41 cases of healthy volunteers as the control group at the same period whose C -reac-tive protein was detected too .The study group was followed up for one year then compared C-reactive protein changes of two groups.Results The C-reactive protein in patients of the study group had average content (15.16 ±7.01)mg/L, which was significantly higher than (4.51 ±1.36)mg/L of the control group,the difference was statistically signifi-cant( t=7.153,P<0.05);The study group of patients with large and medium infarct size ,their C-reactive protein levels were (18.13 ±10.07) mg/L,(15.21 ±7.34) mg/L,significantly greater than patients′with the small size of the infarct(9.95 ±6.14)mg/L,the difference was statistically significant (t=7.316,6.541,all P<0.05);The levels of C-reactive protein in heavy and medium patients were (19.13 ±12.24)mg/L,(16.32 ±8.16)mg/L respectively, significantly higher than the mild patients′(9.93 ±5.41)mg/L,the difference was statistically significant(t=8.153, 7.692,all P<0.05);During follow-up,the serum C-reactive protein levels in patients with recurrence of stroke and death were (16.12 ±8.67)mg/L,(19.17 ±11.36)mg/L,significantly higher than the better prognosis of patients (11.32 ±8.43)mg/L,the difference was statistically significant (t=7.583,8.751,all P<0.05).Conclusion The changes of C-reactive protein levels can be as a prognostic indicator of stroke in clinical .
