CAJ | 학술논문

目的：探讨腹腔镜术后联合低剂量米非司酮治疗子宫内膜异位症周期及临床疗效。方法选取我院收治的66例子宫内膜异位症患者作为研究对象，随机均分为A、B、C三组，A组采用腹腔镜术后米非司酮治疗，B组采用术后孕三烯酮胶囊治疗，C组术后不予以任何辅助药物治疗，比较三组1年内复发率、缓解率、妊娠率、月经恢复时间及排卵恢复时间。结果三组缓解率差异比较无统计学意义（P＞0.05），复发率及妊娠率比较差异有统计学意义（P＜0.05）；A组复发率明显低于B组及C组，妊娠率高于B组及C组，差异有统计学意义（P＜0.05）；A组及C组月经恢复时间及排卵恢复时间明显短于B组，差异比较有统计学意义（P＜0.05）。结论采用腹腔镜术后联合低剂量米非司酮短期疗法治疗子宫内膜异位症有助于缩短月经及排卵恢复时间，提高受孕率，降低复发率，临床疗效显著，值得在临床上推广应用。
목적：탐토복강경술후연합저제량미비사동치료자궁내막이위증주기급림상료효。방법선취아원수치적66례자궁내막이위증환자작위연구대상，수궤균분위A、B、C삼조，A조채용복강경술후미비사동치료，B조채용술후잉삼희동효낭치료，C조술후불여이임하보조약물치료，비교삼조1년내복발솔、완해솔、임신솔、월경회복시간급배란회복시간。결과삼조완해솔차이비교무통계학의의（P＞0.05），복발솔급임신솔비교차이유통계학의의（P＜0.05）；A조복발솔명현저우B조급C조，임신솔고우B조급C조，차이유통계학의의（P＜0.05）；A조급C조월경회복시간급배란회복시간명현단우B조，차이비교유통계학의의（P＜0.05）。결론채용복강경술후연합저제량미비사동단기요법치료자궁내막이위증유조우축단월경급배란회복시간，제고수잉솔，강저복발솔，림상료효현저，치득재림상상추엄응용。
ObjectiveTo evaluate the clinical efficacy of laparoscopic surgery combined with low-dose mifepristone treatment of endometriosis.Methods66 patients with endometriosis in our hospital were randomly divided into A group,B group,C group.A group was given laparoscopic surgery mifepristone treatment,and B group was given gestrinone capsule treatment,and C group wasn't given any secondary therapy.The recurrence rate within 1 year,response rate,pregnancy,menstruation and ovulation recovery time of three groups were compared. Results There was no statistically significant difference in response rates of three groups (P>0.05),and there were significant differences in relapse rate and pregnancy rate(P<0.05).The recurrence rate of A group was significantly lower than that of group B and group C,and the pregnancy rate was higher than that of group B and group C, and there was more significant different(P<0.05).The recovery time of menstruation and ovulation recovery time in A group and group C were significantly shorter than those of group B,and the differences were statistically significant(P<0.05). ConclusionLaparoscopic surgery combined with low-dose mifepristone short-term therapy for endometriosis can help short recovery time of menstruation and ovulation,improve the pregnancy rate,and reduce the relapse rate. It's significant clinical efficacy,worthy of clinical application.