CAJ | 학술논문

目的：探讨参芪花粉片联合β受体阻滞剂治疗血管迷走性晕厥与单用β受体阻滞剂疗效的比较。方法将96例确诊为血管迷走性晕厥的患者随机分为2组，对照组患者服用琥珀酸美托洛尔缓释片，47.5mg/次，1次/d，实验组加用参芪花粉片3.75g/次，2次/d。治疗前及治疗3个月后分别进行直立倾斜试验，同时观察患者晕厥复发情况。结果实验组有效率为85.4%，对照组有效率为70.8%（P＜0.05）。两组治疗前后平均血压差值均数比较治疗组小于对照组（P＜0.05）,平均心率比较治疗组小于对照组（P＞0.05）。结论参芪花粉片联合β受体阻滞剂治疗血管迷走性晕厥的疗效明显优于单用β受体阻滞剂，且有稳定血压作用，药物安全性也更高。
목적：탐토삼기화분편연합β수체조체제치료혈관미주성훈궐여단용β수체조체제료효적비교。방법장96례학진위혈관미주성훈궐적환자수궤분위2조，대조조환자복용호박산미탁락이완석편，47.5mg/차，1차/d，실험조가용삼기화분편3.75g/차，2차/d。치료전급치료3개월후분별진행직립경사시험，동시관찰환자훈궐복발정황。결과실험조유효솔위85.4%，대조조유효솔위70.8%（P＜0.05）。량조치료전후평균혈압차치균수비교치료조소우대조조（P＜0.05）,평균심솔비교치료조소우대조조（P＞0.05）。결론삼기화분편연합β수체조체제치료혈관미주성훈궐적료효명현우우단용β수체조체제，차유은정혈압작용，약물안전성야경고。
Objective To observe the clinical effect of Shenqi pollen plates combined with beta adrenergic antagonists in treatment of vasovagal syncope.Methods 96 vasovagal syncope patients in our hospital were randomly divided into two groups, which were treatment group and control group. Two groups were given metoprolol succinate extended release tablets 47.5mg orally, once a day, additionally, treatment group was given Shenqi pollen plates 3.75g orally, twice a day, and were followed up for 3 months. Head-up tilt testing was performed before treatment and reviewed three months later, moreover, recording the recurrence of syncope.Results The therapeutic efficiency ratio of treatment group was 85.4%,while the control group was 70.8%(P<0.05).Before and after treatment, means of blood pressure difference in treatment group was less than control group(P<0.05), means of heart rate difference in treatment group was less than control group(P>0.05).ConclusionThe therapeutic efficiency of Shenqi pollen plates combined with beta adrenergic antagonists is better than taking beta adrenergic antagonists alone, blood pressure can be more stable, safety can be higher.