CAJ | 학술논문

目的：观察去氧孕烯炔雌醇治疗青春期功能失调性子宫出血（青春期功血）的临床疗效及不良反应。方法将确诊的86例青春期功血患者按照就诊先后分为治疗组和对照组各43例，对照组给予结合型雌激素（倍美力）治疗，治疗组给予去氧孕烯炔雌醇治疗。观察两组的止血效果及药物不良反应。结果治疗组痊愈率为65．1％，对照组为23．3％，两组差异有统计学意义（χ2＝15．28，P＜0．01）；治疗组止血时间为（33．24±12．85）h，短于对照组的（50．31±16．32）h（t＝5．39，P＜0．05）；两组不良反应发生率差异无统计学意义（χ2＝0．49，P＞0．05）。结论去氧孕烯炔雌醇治疗青春期功血的疗效确切，不良反应发生率低，患者接受程度高。
목적：관찰거양잉희결자순치료청춘기공능실조성자궁출혈（청춘기공혈）적림상료효급불량반응。방법장학진적86례청춘기공혈환자안조취진선후분위치료조화대조조각43례，대조조급여결합형자격소（배미력）치료，치료조급여거양잉희결자순치료。관찰량조적지혈효과급약물불량반응。결과치료조전유솔위65．1％，대조조위23．3％，량조차이유통계학의의（χ2＝15．28，P＜0．01）；치료조지혈시간위（33．24±12．85）h，단우대조조적（50．31±16．32）h（t＝5．39，P＜0．05）；량조불량반응발생솔차이무통계학의의（χ2＝0．49，P＞0．05）。결론거양잉희결자순치료청춘기공혈적료효학절，불량반응발생솔저，환자접수정도고。
Objective To observe the clinical efficacy and adverse reactions of desogestrel ethinylestradiol in the treatment of dysfunctional uterine bleeding ( adolescent Dub ) .Methods 86 cases with adolescent functional bleeding were divided into the treatment group and control group ,43 cases in each group .The control group received conjugated estrogen(Premarin) treatment,the treatment group was given desogestrel ethinylestradiol treatment .The hemostatic effect and drug adverse reaction of the two groups were observed .Results The cure rate of the treatment group was 65.1%,that in the control group was 23.3%,there was significant difference between the two groups (χ2 =15.28,P<0.01).The hemostatic time of the treatment group was (33.24 ±12.85)h,which was shorter than (50.31 ± 16.32)h of the control group (t=5.39,P<0.05).The incidence rate of adverse reactions between the two groups had no significant difference (χ2 =0.49,P>0.05).Conclusion Desogestrel ethinylestradiol in the treatment of ado-lescent functional bleeding has exact curative effect ,it has low incidence of adverse reactions and better acceptance .