中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2014年
24期
34-36
,共3页
氨氯地平%阿托伐他汀钙%原发性高血压%肿瘤坏死因子%白介素-6
氨氯地平%阿託伐他汀鈣%原髮性高血壓%腫瘤壞死因子%白介素-6
안록지평%아탁벌타정개%원발성고혈압%종류배사인자%백개소-6
Amlodipine%Atorvastatin calcium%Essential hypertension%Tumor necrosis factor%Interleukin-6
目的：观察氨氯地平与阿托伐他汀钙对原发性高血压患者肿瘤坏死因子和白介素-6的影响。方法将我院收治符合纳入标准的原发性高血压患者80例随机分为观察组和对照组,每组各40例,观察组给予氨氯地平与阿托伐他汀钙治疗,对照组给予氨氯地平治疗,比较两组的疗效及两组患者治疗前后TNF-α和IL-6的变化。结果治疗2个月后,观察组患者的总有效率达92.5%,显著高于对照组,差异有统计学意义(92.5% vs77.5%,P<0.05)。观察组和对照组患者治疗后的SBP、DBP、HR分别明显低于对照组(P<0.05)。且观察组患者治疗后的TNF-α、IL-6分别明显低于对照组(P<0.05)。结论氨氯地平与阿托伐他汀钙联用治疗原发性高血压可以提高疗效,值得临床推广应用。
目的：觀察氨氯地平與阿託伐他汀鈣對原髮性高血壓患者腫瘤壞死因子和白介素-6的影響。方法將我院收治符閤納入標準的原髮性高血壓患者80例隨機分為觀察組和對照組,每組各40例,觀察組給予氨氯地平與阿託伐他汀鈣治療,對照組給予氨氯地平治療,比較兩組的療效及兩組患者治療前後TNF-α和IL-6的變化。結果治療2箇月後,觀察組患者的總有效率達92.5%,顯著高于對照組,差異有統計學意義(92.5% vs77.5%,P<0.05)。觀察組和對照組患者治療後的SBP、DBP、HR分彆明顯低于對照組(P<0.05)。且觀察組患者治療後的TNF-α、IL-6分彆明顯低于對照組(P<0.05)。結論氨氯地平與阿託伐他汀鈣聯用治療原髮性高血壓可以提高療效,值得臨床推廣應用。
목적：관찰안록지평여아탁벌타정개대원발성고혈압환자종류배사인자화백개소-6적영향。방법장아원수치부합납입표준적원발성고혈압환자80례수궤분위관찰조화대조조,매조각40례,관찰조급여안록지평여아탁벌타정개치료,대조조급여안록지평치료,비교량조적료효급량조환자치료전후TNF-α화IL-6적변화。결과치료2개월후,관찰조환자적총유효솔체92.5%,현저고우대조조,차이유통계학의의(92.5% vs77.5%,P<0.05)。관찰조화대조조환자치료후적SBP、DBP、HR분별명현저우대조조(P<0.05)。차관찰조환자치료후적TNF-α、IL-6분별명현저우대조조(P<0.05)。결론안록지평여아탁벌타정개련용치료원발성고혈압가이제고료효,치득림상추엄응용。
Objective To observe the effect of amlodipine and atorvastatin calcium in threatment of patients with hy-pertension and the impact on tumor necrosis factor and interleukin-6. Methods A total of 80 patients with essential hypertension were randomly divided into observation group and control group, each of 40 cases, observation group was given amlodipine and atorvastatin calcium therapy, the control group was given amlodipine treatment groups, efficacy and TNF-αand IL-6 were compared before and after treatment in two groups. Results After 2 months of treatment, the total effective rate of observation group was 92.5%, significantly higher than the control group (92.5% vs 77.5%, P<0.05). Observation group’s SBP, DBP, HR was significantly lower than the control group (P<0.05).After treatment,the TNF-α, IL-6 level of observation group was significantly lower than the control group(P<0.05). Conclusion Amlodip-ine and atorvastatin calcium in treatment of essential hypertension can improve efficacy, worthy of clinical application .
