中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
15期
198-200,216
,共4页
中/长链脂肪乳%结构脂肪乳%危重症%血脂%肝功能
中/長鏈脂肪乳%結構脂肪乳%危重癥%血脂%肝功能
중/장련지방유%결구지방유%위중증%혈지%간공능
Medium and long chain fat emulsion%Structure fat emulsion%Critical illness%Blood lipid%Liver function
目的：探讨结构脂肪乳及中/长链脂肪乳对危重症患者肝功能和血脂的影响。方法采用随机法将98例患者分为两组，即MCT/LCT组与STG组，两组均为49例，两组所患疾病、APACHE II评分、年龄及性别等均无显著性差异（P＞0.05），具有可比性。患者进入ICU后，立即对身体状况及病情进行评估，确定不存在肠外营养支持方面的禁忌证后采用MCT/LCT及STG进行治疗。在第1～2天静脉输注葡萄糖，第3天后开始实施肠外营养支持治疗，两组均连续治疗15d。结果采用两种不同的脂肪乳进行治疗后，两组的AST、TG及TCH、LDL-C差异有统计学意义（P＜0.05），MCT/LCT组的AST、TG、TCH及LDL-C值大于STG组。在HDL-C、DBIL、TBIL、ALP、及ALT方面，治疗前后两组的差异均不明显（P＞0.05）。结论在为危重症患者提供营养支持时，STG对血脂及肝功能各项指标的影响较小，应推广使用STG。
目的：探討結構脂肪乳及中/長鏈脂肪乳對危重癥患者肝功能和血脂的影響。方法採用隨機法將98例患者分為兩組，即MCT/LCT組與STG組，兩組均為49例，兩組所患疾病、APACHE II評分、年齡及性彆等均無顯著性差異（P＞0.05），具有可比性。患者進入ICU後，立即對身體狀況及病情進行評估，確定不存在腸外營養支持方麵的禁忌證後採用MCT/LCT及STG進行治療。在第1～2天靜脈輸註葡萄糖，第3天後開始實施腸外營養支持治療，兩組均連續治療15d。結果採用兩種不同的脂肪乳進行治療後，兩組的AST、TG及TCH、LDL-C差異有統計學意義（P＜0.05），MCT/LCT組的AST、TG、TCH及LDL-C值大于STG組。在HDL-C、DBIL、TBIL、ALP、及ALT方麵，治療前後兩組的差異均不明顯（P＞0.05）。結論在為危重癥患者提供營養支持時，STG對血脂及肝功能各項指標的影響較小，應推廣使用STG。
목적：탐토결구지방유급중/장련지방유대위중증환자간공능화혈지적영향。방법채용수궤법장98례환자분위량조，즉MCT/LCT조여STG조，량조균위49례，량조소환질병、APACHE II평분、년령급성별등균무현저성차이（P＞0.05），구유가비성。환자진입ICU후，립즉대신체상황급병정진행평고，학정불존재장외영양지지방면적금기증후채용MCT/LCT급STG진행치료。재제1～2천정맥수주포도당，제3천후개시실시장외영양지지치료，량조균련속치료15d。결과채용량충불동적지방유진행치료후，량조적AST、TG급TCH、LDL-C차이유통계학의의（P＜0.05），MCT/LCT조적AST、TG、TCH급LDL-C치대우STG조。재HDL-C、DBIL、TBIL、ALP、급ALT방면，치료전후량조적차이균불명현（P＞0.05）。결론재위위중증환자제공영양지지시，STG대혈지급간공능각항지표적영향교소，응추엄사용STG。
Objective To comparative analysis of the influence of structure fat emulsion and medium and long chain fat emulsion to liver function and blood lipid in patients with critical illness. Methods 98 ICU patients were randomLy divided into the MCT/LCT group and the STG group, 49 cases in each group. The disease, APACHE II score, age and gender of two groups were not significant difference (P > 0.05). Two groups were comparable. After entering the ICU, the physical conditions of patients were immediately evaluated and determined that there were not parenteral nutritional support contraindications. The patients were treated with MCT/LCT or STG. The patients were given glucose infusion in the 1-2d, and treated with parenteral nutrition support therapy after 3d. Two groups were treated for 15d. Results After treatment with two different kinds of fat emulsion, there were significant differences between the two groups of AST, TG and TCH, LDL-C(P<0.05). AST, TG, TCH and LDL-C values of the MCT/LCT group were greater than those of STG group. In the HDL-C, DBIL, TBIL, ALP, and ALT of two groups, the differences between before treatment and after treatment were not significant (P>0.05). Conclusion To provide nutritional support for critically ill patients, STG has little effect on the indexes of blood lipid and liver function, should promote the use of STG.
