CAJ | 학술논문

目的：宫颈液基细胞学检查（LPT）与阴道镜检测在宫颈病变早期筛查中的应用效果观察。方法对2010年6月～2013年6月在我院体检科行宫颈癌筛查的735例妇女分别行LPT与阴道镜检测，同时与病理组织学检查结果进行对比分析。结果病理组织检查显示宫颈癌前病变共39例（5.31%），以病理检查结果为金标准，LPT检出符合率为82.05%（32/39）；阴道镜检测检出符合率为61.54%（24/39）；两种方法检出符合率比较差异有统计学意义（x2=4.0519，P＜0.05）；LPT与阴道镜联合检测符合率为100.00%（39/39）。结论宫颈液基细胞学检查与阴道镜检测均能够用于临床宫颈病变的早期筛查，但两者联合应用的效果更加显著，能有效提高宫颈癌及宫颈癌前病变检出率，降低假阴性率，值得在临床推广应用。
목적：궁경액기세포학검사（LPT）여음도경검측재궁경병변조기사사중적응용효과관찰。방법대2010년6월～2013년6월재아원체검과행궁경암사사적735례부녀분별행LPT여음도경검측，동시여병리조직학검사결과진행대비분석。결과병리조직검사현시궁경암전병변공39례（5.31%），이병리검사결과위금표준，LPT검출부합솔위82.05%（32/39）；음도경검측검출부합솔위61.54%（24/39）；량충방법검출부합솔비교차이유통계학의의（x2=4.0519，P＜0.05）；LPT여음도경연합검측부합솔위100.00%（39/39）。결론궁경액기세포학검사여음도경검측균능구용우림상궁경병변적조기사사，단량자연합응용적효과경가현저，능유효제고궁경암급궁경암전병변검출솔，강저가음성솔，치득재림상추엄응용。
Objective To observe the applied effect of cervical liquid-based cytology(LPT) and digital colposcopy in the screening of early cervical lesions. Methods Chose 735 women in the physical examination branch cervical cancer screening from June 2010 to June 2013 in our hospital, then LPT and digital colposcopy was done in these women, at the same time compared and analyzed the histologic examination results. Results After pathologic examination, there were 39 cases of cervical precancerous lesions(5.31%), as the gold standard, the coincidence rate of LPT was 82.05%(32/39); digital colposcope was 61.54%(24/39) ; two methods of detection coincidence rate comparing difference was statistically significant(x2= 4.0519, P<0.05); the detection coincidence rate of LPT cooperate with digital colposcope was 100.00%(39/39). Conclusion LPT and digital colposcopy examination can be used in the screening of early clinical cervical lesions, but the combined effect is more significant. This combination can effectively improve the detection rate of early cervical lesions, reduce false negative rate, and is worth popularizing in clinical application.