CAJ | 학술논문

目的探讨精神分裂症患者内部动机损害及其与心理理论缺陷之间的关系.方法采用精神分裂症内部动机量表(IMI-SR)和心理理论故事图片任务(ToM-PST)对70例精神分裂症患者进行测试,与60例健康对照者作比较.结果患者组IMI-SR总分[(88.43±22.42)分]、兴趣性因子分[(29.11±8.31)分]和选择性因子分[(29.71 ±8.82)分]均低于对照组[分别为(97.77±27.31),(32.03±8.29)和(35.33±9.85)分,P＜0.05 ～0.01].患者组ToM-PST总分[(36.59±11.85)分]显著低于对照组[(57.17±2.08)分,P＜0.01],各因子分组间差异均具有统计学意义(均P＜0.01).相关分析显示,IMI-SR总分与PANSS总分(r=-0.255,P＜0.05)、阴性症状分(r=-0.361,P＜0.01)和阳性症状分(r=-0.298,P＜0.05)呈负相关.患者组IMI-SR总分与ToM-PST总分(r=0.345,P＜0.01)、理解初级信念(r=0.296,P＜0.05)、理解初级错误信念(r=0.243,P＜0.05)、初级信念总分(r=0.311,P＜0.01)、理解次级错误信念(r=0.254,P＜0.05)、次级信念总分(r=0.284,P＜0.05)和理解欺骗(r=0.286,P＜0.05)呈正相关.控制症状评分后,患者组IMI-SR总分与ToM-PST总分及其理解初级信念分、初级信念总分、理解次级信念、次级信念总分和理解欺骗分的相关性仍具统计学意义.结论精神分裂症患者存在内部动机和心理理论损害,患者内部动机障碍和心理理论缺陷可能具有某种共同的病理生理基础.
목적 탐토정신분렬증환자내부동궤손해급기여심리이론결함지간적관계.방법 채용정신분렬증내부동궤량표(IMI-SR)화심리이론고사도편임무(ToM-PST)대70례정신분렬증환자진행측시,여60례건강대조자작비교.결과 환자조IMI-SR총분[(88.43±22.42)분]、흥취성인자분[(29.11±8.31)분]화선택성인자분[(29.71 ±8.82)분]균저우대조조[분별위(97.77±27.31),(32.03±8.29)화(35.33±9.85)분,P＜0.05 ～0.01].환자조ToM-PST총분[(36.59±11.85)분]현저저우대조조[(57.17±2.08)분,P＜0.01],각인자분조간차이균구유통계학의의(균P＜0.01).상관분석현시,IMI-SR총분여PANSS총분(r=-0.255,P＜0.05)、음성증상분(r=-0.361,P＜0.01)화양성증상분(r=-0.298,P＜0.05)정부상관.환자조IMI-SR총분여ToM-PST총분(r=0.345,P＜0.01)、리해초급신념(r=0.296,P＜0.05)、리해초급착오신념(r=0.243,P＜0.05)、초급신념총분(r=0.311,P＜0.01)、리해차급착오신념(r=0.254,P＜0.05)、차급신념총분(r=0.284,P＜0.05)화리해기편(r=0.286,P＜0.05)정정상관.공제증상평분후,환자조IMI-SR총분여ToM-PST총분급기리해초급신념분、초급신념총분、리해차급신념、차급신념총분화리해기편분적상관성잉구통계학의의.결론 정신분렬증환자존재내부동궤화심리이론손해,환자내부동궤장애화심리이론결함가능구유모충공동적병리생리기출.
Objective To explore intrinsic motivation and its relationship to theory of mind in patients with schizophrenia.Methods Seventy schizophrenic patients without treatment and sixty healthy subjects were assessed using the Intrinsic Motivation Inventory for Schizophrenia Research (IMI-SR) and the Theory-of-Mind Picture-Sequencing Task (ToM-PST).Results Compared with healthy subjects,schizophrenic patients showed significantly less IMI-SR total score (97.77 ± 27.31 vs 88.43 ± 22.42,P ＜ 0.01) and subscores of interest (32.03 ± 8.29 vs 29.11 ± 8.31,P ＜ 0.05) and choice (35.33 ± 9.85 vs 29.71 ± 8.82,P ＜ 0.01).Schizophrenic patients also had significantly less total score (36.59 ± 11.85 vs 57.17 ± 2.08,P＜ 0.01) and subscores of ToM-PST compared to normal controls (all P ＜ 0.01).Correlation analysis showed a negative correlation between IMI-SR total score and PANSS total score (r =-0.255,P ＜ 0.05) and the subscores of negative (r =-0.361,P ＜ 0.01)and positive (r =-0.298,P ＜ 0.05) symptoms.There was significantly positive correlation between IMI-SR total score (r =0.345,P ＜0.01) and its subscores of the understanding of first order belief(r =0.296,P ＜ 0.05),the understanding of first order false belief(r =0.243,P ＜ 0.05),first order belief total points (r =0.311,P ＜ 0.01),the understanding of second order false belief(r =0.254,P ＜ 0.05),second order belief total points (r =0.284,P ＜ 0.05),and the understanding of intended deception(r =0.286,P ＜ 0.05) in schizophrenic patients.After controlling for the PANSS total score,the correlation between IMI-SR total score and ToM-PST score and its subscores of the understanding of first order belief,first order belief total points,the understanding of second order belief,second order belief total points,the understanding of intended deception was remain significant.Conclusion Schizophrenic patients had impairments of intrinsic motivation and theory of mind,and intrinsic motivation deficit may shared a common pathophysiological base with the impairment of theory of mind.