CAJ | 학술논문

目的：比较3种不同受精方式的冻融胚胎和囊胚对解冻移植后妊娠结局的影响。方法回顾分析2012年1月至2013年12月在该中心行胚胎解冻移植（FET ）治疗的3586个周期，按受精方式分3组：A组常规体外受精（IVF）冻融胚胎解冻移植2008例、囊胚解冻移植954例；B组卵胞浆单精子注射（ICSI）冻融胚胎解冻移植361例、囊胚解冻移植129例；C组早期补救卵胞浆单精子注射（r-ICSI）冻融胚胎解冻移植87例、囊胚解冻移植47例。比较解冻胚胎和囊胚复苏率、妊娠率、流产率、宫外孕率等指标是否存在差异。结果3种不同受精方式的胚胎和囊胚解冻复苏率、妊娠率、流产率、宫外孕率等比较差异无统计学意义（P＞0．05）。结论与常规体外受精和卵胞浆单精子注射相比，早期补救卵胞浆单精子注射（r-ICSI）是一种有效的治疗手段。
목적：비교3충불동수정방식적동융배태화낭배대해동이식후임신결국적영향。방법회고분석2012년1월지2013년12월재해중심행배태해동이식（FET ）치료적3586개주기，안수정방식분3조：A조상규체외수정（IVF）동융배태해동이식2008례、낭배해동이식954례；B조란포장단정자주사（ICSI）동융배태해동이식361례、낭배해동이식129례；C조조기보구란포장단정자주사（r-ICSI）동융배태해동이식87례、낭배해동이식47례。비교해동배태화낭배복소솔、임신솔、유산솔、궁외잉솔등지표시부존재차이。결과3충불동수정방식적배태화낭배해동복소솔、임신솔、유산솔、궁외잉솔등비교차이무통계학의의（P＞0．05）。결론여상규체외수정화란포장단정자주사상비，조기보구란포장단정자주사（r-ICSI）시일충유효적치료수단。
Objective To compare the effect of three different fertilization modes of frozen-thawed embryos and blastocysts on the pregnancy outcome after thawed transplantation .Methods 3 586 cycles of frozen embryos transplantation (FET ) treatment in our center from January 2012 to December 2013 were retrospectively analyzed and divided into 3 groups according to the fertilization modes .The group A adopted the conventional in vitro fertilization (IVF) of frozen-thawed embryo transfer in 2 008 cases and blas-tocysts transfer in 954 cases .The group B adopted intracytoplasmic sperm injection (ICSI) of frozen-thawed embryo transfer in 361 cases and blastocysts transfer in 129 cases ;the group C was given early remedy intracytoplasmic sperm injection (r-ICSI) of frozen-thawed embryo transfer in 87 cases and blastocysts transfer in 47 cases .The recovery rate of embryo and blastocyst ,pregnancy rate ,abortion rate ,ectopic pregnancy rate were compared for determining whether the differences among the indexes existed . Results The thawing recovery rate ,pregnancy rate ,abortion rate and ectopic pregnancy rate in the three different fertilization modes of embryo and blastocyst had no statistically significant differences (P>0 .05) .Conclusion Compared with conventional in vitro fertilization and intracytoplasmic sperm injection ,early r-ICSI is one of effective treatment means .