实用医学杂志
實用醫學雜誌
실용의학잡지
THE JOURNAL OF PRACTICAL MEDICINE
2014年
15期
2411-2414
,共4页
乳腺肿瘤%磁共振波谱%弥散%动态增强
乳腺腫瘤%磁共振波譜%瀰散%動態增彊
유선종류%자공진파보%미산%동태증강
Breast neoplasms%Magnetic resonance spectroscopy%Dispersion%Dynamic contrast enhancement
目的：探讨形态学基础上磁共振功能成像（氢质子波谱、弥散、MR动态增强）在乳腺肿瘤诊断中的优化组合及价值。方法：收集2009-2013年来我院经临床及病理诊断为乳腺肿瘤的患者140例，其中恶性肿瘤63例，良性肿瘤77例，且同时行基础扫描、1H-MRS、DWI 及动态增强检查的患者资料，将所得图像信息分析，并与病理结果比较，得出基础图像上波谱、弥散、动态增强两两组合信息对乳腺癌诊断的敏感性、特异性、准确性。结果：所有病例均病理证实。基础图上DWI、动态增强组合检查诊断乳腺癌的敏感性89．8％，特异性90．1％，准确性90．0％；MRS、动态组合检查诊断乳腺癌的敏感性为77．9％，特异性77．3％，准确性79．3％；DWI、MRS 联合检查诊断乳腺癌的敏感性76．3％，特异性77．8％，准确性77．1％；3种组合检查诊断乳腺癌结果比较，χ2＝9．057，P＝0．011，差异有显著性。结论：基础图像上DWI与动态增强组合对乳腺肿瘤诊断的敏感性、特异性及准确性最高，可以作为乳腺肿瘤功能成像最佳组合。
目的：探討形態學基礎上磁共振功能成像（氫質子波譜、瀰散、MR動態增彊）在乳腺腫瘤診斷中的優化組閤及價值。方法：收集2009-2013年來我院經臨床及病理診斷為乳腺腫瘤的患者140例，其中噁性腫瘤63例，良性腫瘤77例，且同時行基礎掃描、1H-MRS、DWI 及動態增彊檢查的患者資料，將所得圖像信息分析，併與病理結果比較，得齣基礎圖像上波譜、瀰散、動態增彊兩兩組閤信息對乳腺癌診斷的敏感性、特異性、準確性。結果：所有病例均病理證實。基礎圖上DWI、動態增彊組閤檢查診斷乳腺癌的敏感性89．8％，特異性90．1％，準確性90．0％；MRS、動態組閤檢查診斷乳腺癌的敏感性為77．9％，特異性77．3％，準確性79．3％；DWI、MRS 聯閤檢查診斷乳腺癌的敏感性76．3％，特異性77．8％，準確性77．1％；3種組閤檢查診斷乳腺癌結果比較，χ2＝9．057，P＝0．011，差異有顯著性。結論：基礎圖像上DWI與動態增彊組閤對乳腺腫瘤診斷的敏感性、特異性及準確性最高，可以作為乳腺腫瘤功能成像最佳組閤。
목적：탐토형태학기출상자공진공능성상（경질자파보、미산、MR동태증강）재유선종류진단중적우화조합급개치。방법：수집2009-2013년래아원경림상급병리진단위유선종류적환자140례，기중악성종류63례，량성종류77례，차동시행기출소묘、1H-MRS、DWI 급동태증강검사적환자자료，장소득도상신식분석，병여병리결과비교，득출기출도상상파보、미산、동태증강량량조합신식대유선암진단적민감성、특이성、준학성。결과：소유병례균병리증실。기출도상DWI、동태증강조합검사진단유선암적민감성89．8％，특이성90．1％，준학성90．0％；MRS、동태조합검사진단유선암적민감성위77．9％，특이성77．3％，준학성79．3％；DWI、MRS 연합검사진단유선암적민감성76．3％，특이성77．8％，준학성77．1％；3충조합검사진단유선암결과비교，χ2＝9．057，P＝0．011，차이유현저성。결론：기출도상상DWI여동태증강조합대유선종류진단적민감성、특이성급준학성최고，가이작위유선종류공능성상최가조합。
Objective To investigate the optimal combination and the value of functional magnetic resonance imaging in the diagnosis of breast tumors. Methods One hundred and forty patients who had been clinically and pathologically diagnosed as breast tumors in our hospital during the period of 2009 to 2013 were collected. 63 of whom had breast cancer and 77 had benign tumor. All the patients received 1H-MRS, DWI and dynamic enhanced MRI at the same time. The obtained images were analyzed and then compared with the pathological findings. The accuracy, sensitivity, and specificity of MRS combined with DWI or dynamic enhanced MRI, or DwI combined with enhanced MRI in the diagnosis of breast cancer were obtained. Results All the diagnosis were pathologically confirmed. The accuracy, sensitivity, and specificity were 89.8%, 90.1%, and 90.0% for DWI combined with dynamic contrast-enhanced MRI; 77.9%, 77.3% and 79.3% for MRS in combination with enhanced MRI; and 76.3%, 77.8% and 77.1% for DWI combined with MRS. There were significant differences among the three kinds of combination detection in diagnosis of breast cancer , χ2= 9.057, P = 0.011. Conclusions The sensitivity, specificity and accuracy is the highest in DWI combined with dynamic enhanced MRI in the diagnosis of breast tumor , which can be used as the best combination imaging for breast tumor.
