CAJ | 학술논문

目的：探讨肝素锂抗凝血浆代替血清在生化检验中的可行性。方法对比测定了100例肝素锂抗凝血浆和血清标本的54项生化指标。结果丙氨酸转移酶（ALT）等45项生化指标抗凝血浆与血清测定结果差异无统计学意义（P＞0．05）；总蛋白（TP）、钾离子（K＋）、乳酸脱氢酶（LDH）、葡萄糖（GLU）、肌酸激酶同工酶（CK-MB）、脂肪酶（LPS）结果比较，差异有统计学意义（P＜0．05），但结果相关性好（r值最大0．998，最小0．887）；转铁蛋白（TRF）、α-L-岩藻糖苷酶（AFU）、亮氨酸转肽酶（LAP）3项比较，差异有统计学意义（P＜0．01），无相关性（r＜0．6）。结论肝素锂具有抗凝能力强，不影响细胞体积，不溶血等优点，除AFU、TRF、LAP不宜检测外，可用于常规生化检验，特别适合用于门诊、急诊和凝血功能异常的患者。
목적：탐토간소리항응혈장대체혈청재생화검험중적가행성。방법대비측정료100례간소리항응혈장화혈청표본적54항생화지표。결과병안산전이매（ALT）등45항생화지표항응혈장여혈청측정결과차이무통계학의의（P＞0．05）；총단백（TP）、갑리자（K＋）、유산탈경매（LDH）、포도당（GLU）、기산격매동공매（CK-MB）、지방매（LPS）결과비교，차이유통계학의의（P＜0．05），단결과상관성호（r치최대0．998，최소0．887）；전철단백（TRF）、α-L-암조당감매（AFU）、량안산전태매（LAP）3항비교，차이유통계학의의（P＜0．01），무상관성（r＜0．6）。결론간소리구유항응능력강，불영향세포체적，불용혈등우점，제AFU、TRF、LAP불의검측외，가용우상규생화검험，특별괄합용우문진、급진화응혈공능이상적환자。
Objective To explore the feasibility of lithium heparin anticoagulant plasma instead of serum in biochemical test . Methods 54 biochemical indexes were comparatively detected in 100 samples of lithium heparin anticoagulant plasma and serum . Results The detection results of 45 biochemical indexes in 100 samples of lithium heparin anticoagulant blood plasma and serum showed no statistically significant differences (P>0 .05) .There were statistically significant differences in the indexes of total pro-tein(TP) ,potassium ion(K+ ) ,lactic dehydrogenase(LDH) ,glucose(GLU) ,creatine kinase-MB(CK-MB) and lipase(LPS) between lithium heparin anticoagulant plasma and serum(P<0 .05) ,while results showed good correlation(the maximum r value was 0 .998 , the minimum r value was 0 .887);3 indexes of transferrin(TRF) ,α-L-fucosidase(AFU) and leucine aminopeptidase (LAP) had statistically significant differences (P<0 .05) and showed no correlation(r<0 .6) .Conclusion Lithium heparin has the strongly an-ticoagulant ability with the advantages of non-influence on cell volume and no hemolysis ,which can be used for routine biochemical test ,especially suitable for the outpatient service ,emergency and the patients with blood coagulation dysfunction ,but the detection of TRF ,AFU and LAP can not be suitable .