中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2014年
22期
12-13
,共2页
淋球菌%抗生素%敏感性
淋毬菌%抗生素%敏感性
림구균%항생소%민감성
Neisseria gonorrhoeae%Antibiotics%Susceptibility
目的：了解江门地区2010年~2012年淋球菌对抗生素的敏感性及变化趋势。方法采用琼脂稀释法测定6种抗生素对127株淋球菌的最小抑菌浓度（MIC）及质粒介导的高度耐四环素淋球菌（TRNG），采用纸片酸度法检测菌株是否产β-内酰胺酶（PPNG）。结果淋球菌对大观霉素及头孢克肟的敏感率均为100%，头孢曲松为77.95%，环丙沙星敏感率最低，其耐药率高达92.13%；127株淋球菌中检出PPNG菌株48株（37.80%），TRNG菌株51株（40.16%）。结论淋球菌对青霉素、四环素和环丙沙星的耐药率较高，大观霉素及头孢克肟可作为治疗本地区淋病的首选药物。
目的：瞭解江門地區2010年~2012年淋毬菌對抗生素的敏感性及變化趨勢。方法採用瓊脂稀釋法測定6種抗生素對127株淋毬菌的最小抑菌濃度（MIC）及質粒介導的高度耐四環素淋毬菌（TRNG），採用紙片痠度法檢測菌株是否產β-內酰胺酶（PPNG）。結果淋毬菌對大觀黴素及頭孢剋肟的敏感率均為100%，頭孢麯鬆為77.95%，環丙沙星敏感率最低，其耐藥率高達92.13%；127株淋毬菌中檢齣PPNG菌株48株（37.80%），TRNG菌株51株（40.16%）。結論淋毬菌對青黴素、四環素和環丙沙星的耐藥率較高，大觀黴素及頭孢剋肟可作為治療本地區淋病的首選藥物。
목적：료해강문지구2010년~2012년림구균대항생소적민감성급변화추세。방법채용경지희석법측정6충항생소대127주림구균적최소억균농도（MIC）급질립개도적고도내사배소림구균（TRNG），채용지편산도법검측균주시부산β-내선알매（PPNG）。결과림구균대대관매소급두포극우적민감솔균위100%，두포곡송위77.95%，배병사성민감솔최저，기내약솔고체92.13%；127주림구균중검출PPNG균주48주（37.80%），TRNG균주51주（40.16%）。결론림구균대청매소、사배소화배병사성적내약솔교고，대관매소급두포극우가작위치료본지구임병적수선약물。
Objective To survey the susceptibility and trend of Neisseria gonorrhoeae to antibioticagets in Jiangmen from 2010 to 2012.Methods 127 Neisseria gonorrhoeae strains were observed for their susceptibility to six antibiotics, agard lution method was used to detect minimal inhibitory concentration (MIC) of antimicrobial agents and high-level tetracycline-resistance of Neisseria gonorrhoeae(TRNG),the production ofβ-lactamase was dectermined by paper acidometric method. Results The percentage of Neisseria gonorrhoeae strains sensitive to Spectinomycin,cefixime and ceftriaxone was 100%,100%and 77.95%,the percentage of Neisseria gonorrhoeae strains resistent to ciprofloxacin was 92.13%;48(37.80%) strains were penicillinase-producing Neisseria gonorrhoeae (PPNG),51(40.16%) strains were TRNG. Conclusion The Neisseria gonorrhoeae isolates are highly resistant to penicillin,tetracycline and ciprof loxacin,spectinomycin and cefixime should be used the first-line drugs for the treatment of Neisseria gonorrhoeae in Jiangmen.
