CAJ | 학술논문

目的：对比分析住院的4种常见非感染性肝病患者的临床特征及近10年来的变化趋势。方法采用 SPSS18.0软件对近10年收治的12508例各种非感染性肝病患者的临床特征及变化趋势进行对比分析。结果酒精性肝病和自身免疫性肝病患者较多，分别占非感染性肝病患者的35.1%和32.1%；住院的酒精性肝病、药物性肝损伤和自身免疫性肝病患者占总的住院肝病患者的比例逐年上升，10年间分别上升了2.4倍、2.3倍和2.1倍；酒精性肝病和非酒精性脂肪性肝病患者男性占绝大多数，分别为97.7%和77.7%，而自身免疫性肝病和药物性肝损伤患者女性占绝大多数，分别为84.3%和57.9%（P＜0.01）；自身免疫性肝病患者平均年龄为（47.6±10.6岁），非酒精性脂肪性肝病患者平均年龄为[（35.9±14.1）岁，P＜0.01]，酒精性肝病和药物性肝损害患者年龄分布集中在40～49岁，分别占37.1%和25.0%，而自身免疫性肝病和非酒精性脂肪性肝病患者年龄分别集中在50～59岁和30～39岁，分别占33.7%和25.3%（P＜0.01）。结论住院的非感染性肝病患者占住院肝病患者的比例在不断上升，须重视该类疾病的诊治，加强早期干预。
목적：대비분석주원적4충상견비감염성간병환자적림상특정급근10년래적변화추세。방법채용 SPSS18.0연건대근10년수치적12508례각충비감염성간병환자적림상특정급변화추세진행대비분석。결과주정성간병화자신면역성간병환자교다，분별점비감염성간병환자적35.1%화32.1%；주원적주정성간병、약물성간손상화자신면역성간병환자점총적주원간병환자적비례축년상승，10년간분별상승료2.4배、2.3배화2.1배；주정성간병화비주정성지방성간병환자남성점절대다수，분별위97.7%화77.7%，이자신면역성간병화약물성간손상환자녀성점절대다수，분별위84.3%화57.9%（P＜0.01）；자신면역성간병환자평균년령위（47.6±10.6세），비주정성지방성간병환자평균년령위[（35.9±14.1）세，P＜0.01]，주정성간병화약물성간손해환자년령분포집중재40～49세，분별점37.1%화25.0%，이자신면역성간병화비주정성지방성간병환자년령분별집중재50～59세화30～39세，분별점33.7%화25.3%（P＜0.01）。결론주원적비감염성간병환자점주원간병환자적비례재불단상승，수중시해류질병적진치，가강조기간예。
Objective To analyze the clinical features of inpatients with top four kinds of non-infectious liver diseases (NILD) and changing trend of the disease spectrums over the past decade. Methods The clinical data of 12508 of inpatients with NILD in our hospital in the past decade were collected and analyzed with SPSS18.0. The clinical features and changing trend in disease spectrum were explored. Results Patients with alcoholic liver diseases and autoimmune liver diseases accounted for 35.0% and 32.1%,respectively;the ratio of inpatients with alcoholic liver diseases,drug-induced liver injury and autoimmune liver diseases to total inpatients with liver diseases increased 2.4,2.3 and 2.1 -fold,respectively over the past decade;the percentage of male patients with alcoholic liver diseases and non-alcoholic fatty liver diseases accounted for 97.7% and 77.7% , respectively,while the percentage of female patients accounted for 84.3% and 57.9% ,respectively (P<0.01)in patients with autoimmune liver diseases and drug -induced liver injury;the average age of patients with autoimmune liver diseases was(47.6±10.6)years,while it was [(35.9±14.1) years,P<0.01)in patients with non-alcoholic fatty liver diseases;the patients in the age range of 40 to 49 years accounted for 37.1% and 25.0%, respectively,in patients with alcoholic liver diseases and drug-induced liver disease,while the patients in the age range of 50 to 59 years and 30 to 39 years accounted for 33.7% and 25.3%,respectively (P<0.01)in patients with autoimmune liver diseases and non-alcoholic fatty liver diseases. Conclusions The ratio of patients with NILD to total patients with liver diseases is increasing gradually over the past decade and more attention should be paid for the management of those patients.