CAJ | 학술논문

目的：了解中国近10年在非酒精性脂肪性肝病（NAFLD）领域的研究热点和主题结构。方法以2014年2月为检索节点，对“中国科技引文数据库（CSCD）”中2004年1月～2013年12月所收录的有关 NAFLD研究文献中的关键词作为研究对象，采用词频分析、因子分析和共词聚类分析等方法，应用 Excel 2010和 SPSS17.0统计软件对这些关键词进行统计分析。结果共检索到标注关键词的 NAFLD 相关文献852篇，截取的40个高频关键词涵盖全部相关论文数的70.2%；经共词聚类分析归纳出有关 NAFLD 研究中的9个研究热点：胰岛素增敏药物、超声检查、流行病学及危险因素、动物模型、发病机制及中医药疗法、胰岛素抵抗、中医药研究、基因水平和临床诊治研究。结论本文归纳出的9个研究热点涵盖了近10年在 NAFLD 研究领域的中文文献，了解它们的进展有助于相关研究的扩展。
목적：료해중국근10년재비주정성지방성간병（NAFLD）영역적연구열점화주제결구。방법이2014년2월위검색절점，대“중국과기인문수거고（CSCD）”중2004년1월～2013년12월소수록적유관 NAFLD연구문헌중적관건사작위연구대상，채용사빈분석、인자분석화공사취류분석등방법，응용 Excel 2010화 SPSS17.0통계연건대저사관건사진행통계분석。결과공검색도표주관건사적 NAFLD 상관문헌852편，절취적40개고빈관건사함개전부상관논문수적70.2%；경공사취류분석귀납출유관 NAFLD 연구중적9개연구열점：이도소증민약물、초성검사、류행병학급위험인소、동물모형、발병궤제급중의약요법、이도소저항、중의약연구、기인수평화림상진치연구。결론본문귀납출적9개연구열점함개료근10년재 NAFLD 연구영역적중문문헌，료해타문적진전유조우상관연구적확전。
Objective To explore the research hotspots and subject structure of non-alcoholic fatty liver diseases (NAFLD) in China in the past decade. Methods The key words of articles in NAFLD field were retrieved in Chinese science citation database (CSCD) from January 2004 to December 2013. Word-frequency analysis,factor analysis and co-words clustered analysis were applied and statistic analysis was performed using excell2010 and SPSS17.0. Results Eight hundred and fifty-two articles in presence of keywords about NAFLD were included and 40 high-frequency words were selected,which accounted for 70.2% of all relevant papers. The co-word clustered analysis showed that there were 9 hot subjects about NAFLD during last 10 years including insulin-sensitizing drugs,ultrasonography,epidemiology and risk factors,animal models,pathogenesis and traditional Chinese medicine,insulin resistance,Chinese medicine research,as well as gene and clinical treatment studies. Conclusions The co-word clustered analysis of research hotspots helps to understand the developmental of NAFLD in China.