CAJ | 학술논문

目的：观察肺痿冲剂方治疗特发性肺纤维化肺肾两虚，气虚血瘀证患者的临床疗效。方法：将40例患者随机分为2组，治疗组以肺痿冲剂方治疗，对照组予口服金水宝胶囊，观察2组患者临床疗效、中医单项症状积分、肺功能、HRCT评分、圣乔治生活质量问卷以及6分钟步行试验。结果：在中医单项症状疗效积分（活动后气促、疲倦乏力）、肺功能中一氧化碳弥散量、蜂窝网评分及6分钟步行试验等方面，治疗组改善情况优于对照组，6个月、3个月疗程比较上述趋势更明显。结论：肺痿冲剂方治疗特发性肺纤维化肺肾两虚，气虚血瘀证，在改善临床症状、改善肺弥散功能、延缓蜂窝肺进展、改善生活质量及活动耐力等方面有较显著疗效。
목적：관찰폐위충제방치료특발성폐섬유화폐신량허，기허혈어증환자적림상료효。방법：장40례환자수궤분위2조，치료조이폐위충제방치료，대조조여구복금수보효낭，관찰2조환자림상료효、중의단항증상적분、폐공능、HRCT평분、골교치생활질량문권이급6분종보행시험。결과：재중의단항증상료효적분（활동후기촉、피권핍력）、폐공능중일양화탄미산량、봉와망평분급6분종보행시험등방면，치료조개선정황우우대조조，6개월、3개월료정비교상술추세경명현。결론：폐위충제방치료특발성폐섬유화폐신량허，기허혈어증，재개선림상증상、개선폐미산공능、연완봉와폐진전、개선생활질량급활동내력등방면유교현저료효。
Objective:To investigate the clinical effect of Feiwei medicinal instant graneles on patients with idiopathic pulmonary with syndromes of lung-kidney deficiency &qi deficiency with blood stasis.Methods:Forty patients were randomly divided into the treatment group given the treatment of Feiwei medicinal instant granuels and control group given the treatment of Jinshuibao capsule.Some out-comes were observed in 2 groups including the CRP score,the TCM individual symptome integration,the 1 ung function,HRCT findings scores,the St.George 1 ife quality questionnaire and the6-min walk test.Results:Compared with patients in the control group,patients in the treatment group had better improvement in terms of the CRP score,cumulative points of efficacy for individual Chinese medicine symptoms(Shortness of breath after activities,fatigue),DLCO in the function,honeycombing scores,St.George life quality questionnaire and the six-min walk test.Moreover,on the sixth month,most of those outcomes were better than those of the third month.Conclusion:Feiwei medicinal instant granuels treating idiopathic pulmonary fibrosis patients with syndromes of lung-kidney deficiency&qi deficiency with blood stasis has a significant effect in improving clinical symptoms,life qualities and increasing activity tolerance.