无机化学学报
無機化學學報
무궤화학학보
JOURNAL OF INORGANIC CHEMISTRY
2014年
7期
1733-1740
,共8页
Keypour Hassan%Liyaghati-Delshad Mozhdeh%Rezaeivala Majid%Khavasi Hamid Reza
Keypour Hassan%Liyaghati-Delshad Mozhdeh%Rezaeivala Majid%Khavasi Hamid Reza
Keypour Hassan%Liyaghati-Delshad Mozhdeh%Rezaeivala Majid%Khavasi Hamid Reza
大环配体%席夫碱%锰(Ⅱ)配合物%抗菌活性%质子化常数
大環配體%席伕堿%錳(Ⅱ)配閤物%抗菌活性%質子化常數
대배배체%석부감%맹(Ⅱ)배합물%항균활성%질자화상수
macrocyclic ligand%Schiff base%manganese(Ⅱ) complex%antibacterial effect%protonation constant
在Mn(Ⅱ)模板作用下,2,6-diacetylpyridine (DAP)及合适链状胺化合物通过[1+1]环缩合反应,合成了3个大环席夫碱配合物,并进行了红外、元素分析、质谱及电导率等表征及研究.测得了配合物[MnL1(CH3CN)](Cl04)2的晶体结构,中心离子呈现出稍微扭曲的五角锥配位构型.研究了配合物对S.aureus (ATCC 6633),B.cereus (ATCC 7064),C.xerosis (ATCC 373)(gram-positive bacterial strains),E.coli (PTCC 10009),K.pneuomoniae (MTCC 109),and P.vulgaris (lio)(gram-negative bacterial strains)的抗菌活性.结果显示[MnL3](ClO4)2抗菌活性明显优于[MnL1(CH3CN)](ClO4)2 and [MnL2](ClO4)2.在25℃条件下0.1 mol· L-1 KCl溶液中,通过电位计量法测定了化合物的质子化常数.
在Mn(Ⅱ)模闆作用下,2,6-diacetylpyridine (DAP)及閤適鏈狀胺化閤物通過[1+1]環縮閤反應,閤成瞭3箇大環席伕堿配閤物,併進行瞭紅外、元素分析、質譜及電導率等錶徵及研究.測得瞭配閤物[MnL1(CH3CN)](Cl04)2的晶體結構,中心離子呈現齣稍微扭麯的五角錐配位構型.研究瞭配閤物對S.aureus (ATCC 6633),B.cereus (ATCC 7064),C.xerosis (ATCC 373)(gram-positive bacterial strains),E.coli (PTCC 10009),K.pneuomoniae (MTCC 109),and P.vulgaris (lio)(gram-negative bacterial strains)的抗菌活性.結果顯示[MnL3](ClO4)2抗菌活性明顯優于[MnL1(CH3CN)](ClO4)2 and [MnL2](ClO4)2.在25℃條件下0.1 mol· L-1 KCl溶液中,通過電位計量法測定瞭化閤物的質子化常數.
재Mn(Ⅱ)모판작용하,2,6-diacetylpyridine (DAP)급합괄련상알화합물통과[1+1]배축합반응,합성료3개대배석부감배합물,병진행료홍외、원소분석、질보급전도솔등표정급연구.측득료배합물[MnL1(CH3CN)](Cl04)2적정체결구,중심리자정현출초미뉴곡적오각추배위구형.연구료배합물대S.aureus (ATCC 6633),B.cereus (ATCC 7064),C.xerosis (ATCC 373)(gram-positive bacterial strains),E.coli (PTCC 10009),K.pneuomoniae (MTCC 109),and P.vulgaris (lio)(gram-negative bacterial strains)적항균활성.결과현시[MnL3](ClO4)2항균활성명현우우[MnL1(CH3CN)](ClO4)2 and [MnL2](ClO4)2.재25℃조건하0.1 mol· L-1 KCl용액중,통과전위계량법측정료화합물적질자화상수.
