海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2014年
16期
2375-2377
,共3页
高危孕妇%产前诊断%妊娠期糖尿病%二次葡萄糖筛查
高危孕婦%產前診斷%妊娠期糖尿病%二次葡萄糖篩查
고위잉부%산전진단%임신기당뇨병%이차포도당사사
Risk pregnant women%Prenatal diagnosis%Gestational diabetes%Repeated oral glucose tolerance tests
目的：研究行多次OGTT检查对高危孕妇产前诊断妊娠期糖尿病的临床应用价值，并探讨母婴结局。方法简单随机选择2012年8~11月于湖南省妇幼保健院产科门诊行产前捡查的62例高危孕妇(观察组)，分别于孕24~28周及32~35周进行75 g口服葡萄糖量试验检查。选择同期未按照医嘱及时复查的高危孕妇39例为对照组，观察高危孕妇二次筛查妊娠期糖尿病的检出率及两组孕妇胎盘异常或早产、新生儿Apgar评分和住院时间。结果高危孕妇二次葡萄糖筛查的检出率为16.13%(10/62)，明显高于首次葡萄糖筛查的检出率4.84%(3/62)，差异有统计学意义(P<0.05)。观察组新生儿Apgar评分为(8.89±0.06)分，高于对照组的(8.25±0.04)分，差异有统计学意义(P<0.05)；观察组产妇和婴儿平均住院时间为(6.12±0.08) d，低于对照组的(8.61±0.17) d，差异也有统计学意义(P<0.05)。结论对高危孕妇增加二次葡萄糖筛查可以提高妊娠期糖尿病的检出率，为患者的早期诊断和治疗提供更合适的依据，明显改善母婴结局，适合临床推广应用。
目的：研究行多次OGTT檢查對高危孕婦產前診斷妊娠期糖尿病的臨床應用價值，併探討母嬰結跼。方法簡單隨機選擇2012年8~11月于湖南省婦幼保健院產科門診行產前撿查的62例高危孕婦(觀察組)，分彆于孕24~28週及32~35週進行75 g口服葡萄糖量試驗檢查。選擇同期未按照醫囑及時複查的高危孕婦39例為對照組，觀察高危孕婦二次篩查妊娠期糖尿病的檢齣率及兩組孕婦胎盤異常或早產、新生兒Apgar評分和住院時間。結果高危孕婦二次葡萄糖篩查的檢齣率為16.13%(10/62)，明顯高于首次葡萄糖篩查的檢齣率4.84%(3/62)，差異有統計學意義(P<0.05)。觀察組新生兒Apgar評分為(8.89±0.06)分，高于對照組的(8.25±0.04)分，差異有統計學意義(P<0.05)；觀察組產婦和嬰兒平均住院時間為(6.12±0.08) d，低于對照組的(8.61±0.17) d，差異也有統計學意義(P<0.05)。結論對高危孕婦增加二次葡萄糖篩查可以提高妊娠期糖尿病的檢齣率，為患者的早期診斷和治療提供更閤適的依據，明顯改善母嬰結跼，適閤臨床推廣應用。
목적：연구행다차OGTT검사대고위잉부산전진단임신기당뇨병적림상응용개치，병탐토모영결국。방법간단수궤선택2012년8~11월우호남성부유보건원산과문진행산전검사적62례고위잉부(관찰조)，분별우잉24~28주급32~35주진행75 g구복포도당량시험검사。선택동기미안조의촉급시복사적고위잉부39례위대조조，관찰고위잉부이차사사임신기당뇨병적검출솔급량조잉부태반이상혹조산、신생인Apgar평분화주원시간。결과고위잉부이차포도당사사적검출솔위16.13%(10/62)，명현고우수차포도당사사적검출솔4.84%(3/62)，차이유통계학의의(P<0.05)。관찰조신생인Apgar평분위(8.89±0.06)분，고우대조조적(8.25±0.04)분，차이유통계학의의(P<0.05)；관찰조산부화영인평균주원시간위(6.12±0.08) d，저우대조조적(8.61±0.17) d，차이야유통계학의의(P<0.05)。결론대고위잉부증가이차포도당사사가이제고임신기당뇨병적검출솔，위환자적조기진단화치료제공경합괄적의거，명현개선모영결국，괄합림상추엄응용。
Objective To study the clinical value of repeated OGTTs in prenatal diagnosis of gestational dia-betes in high-risk pregnant women and explore the pregnancy outcome. Methods Sixty-two cases of high-risk preg-nant women were selected in Department of obstetrics of Maternal and Child Health Hospital of Hunan Province from Aug. 2012 to Nov. 2012 (the observation group). They were carried oral glucose tolerance tests at 24~28 weeks and 32~35 weeks. Thirty-nine high-risk pregnant women, which did not follow the doctors' instruction to repeat the test, were selected during the same period as the control group. The detection rate of gestational diabetes in high risk preg-nant women after twice screening was observed, and compare the placental abnormality, premature delivery, neonatal Apgar score and hospitalization time of two groups were compared. Results The detection rate of the second oral glucose tolerance test in high-risk pregnant was statistically significantly higher than the initial detection rate (16.13%vs 4.84%, P<0.05). The neonatal Apgar score of the observation group was significantly higher than that of the control group [(8.89±0.06) vs (8.25± 0.04), P<0.05]. Average maternal and infant hospitalization time of the observation group was significantly lower than that of the control group [(6.12±0.08) d vs (8.61±0.17) d, P<0.05]. Conclusion Re-peated oral glucose tolerance tests in high-risk pregnant women can increase the detection rate of gestational diabetes, and provide evidence for early diagnosis and treatment of gestational diabetes in patients, which will improve maternal and neonatal outcomes and is suitable for clinical application.
