CAJ | 학술논문

目的：探讨急性生理学与慢性健康状况评分Ⅱ（APACHEⅡ评分）对急性重症有机磷中毒患者预后判断的价值。方法选择急性重症有机磷中毒患者42例，其中存活34例、死亡8例，收集患者入院后24 h内APACHEⅡ评分，并进行受试者工作特征曲线（ROC曲线）分析。结果42例急性重症有机磷中毒患者APACHEⅡ评分为18～30分，平均（20．11±6．32）分，其中存活组为（16．10±3．12）分、死亡组为（28．01±4．46）分，两组比较差异有统计学意义（P＜0．01）。随着APACHEⅡ评分的增高，急性重症有机磷中毒患者病死率逐渐升高，APACHEⅡ评分对死亡判断的ROC曲线下总面积为0．922，APACHEⅡ评分21．2分为最佳诊断界点，其敏感性和特异性分别为95％、89％。结论 APACHEⅡ评分能预测急性重症有机磷中毒患者的严重程度，并可以协助判断患者预后，APACHEⅡ评分大于或等于21．2分可作为患者死亡的预警指标。
목적：탐토급성생이학여만성건강상황평분Ⅱ（APACHEⅡ평분）대급성중증유궤린중독환자예후판단적개치。방법선택급성중증유궤린중독환자42례，기중존활34례、사망8례，수집환자입원후24 h내APACHEⅡ평분，병진행수시자공작특정곡선（ROC곡선）분석。결과42례급성중증유궤린중독환자APACHEⅡ평분위18～30분，평균（20．11±6．32）분，기중존활조위（16．10±3．12）분、사망조위（28．01±4．46）분，량조비교차이유통계학의의（P＜0．01）。수착APACHEⅡ평분적증고，급성중증유궤린중독환자병사솔축점승고，APACHEⅡ평분대사망판단적ROC곡선하총면적위0．922，APACHEⅡ평분21．2분위최가진단계점，기민감성화특이성분별위95％、89％。결론 APACHEⅡ평분능예측급성중증유궤린중독환자적엄중정도，병가이협조판단환자예후，APACHEⅡ평분대우혹등우21．2분가작위환자사망적예경지표。
Objective To explore the prognostic value of APACHE Ⅱscore in patients with Severe acute organophosphorus poi-soning .Methods 42 patients with Severe acute organophosphorus poisoning ,in which 34 cases survived ,8 cases dead ,were select-ed .The APACHE Ⅱscores of patients in first 24 h of admission were collected ,and receiver operating characteristic curves (ROC curve) were drawn .Results APACHE Ⅱ score of the 42 patients with Severe acute organophosphorus poisoning was 18 ~30 (20 .11 ± 6 .32) ,in which the survival group was(16 .10 ± 3 .12) ,the dead group was(28 .01 ± 4 .46) (P<0 .01) .With the increase of APACHE Ⅱ score ,the fatality rate gradually increased .The total area under the ROC curves of APACHE Ⅱ score for death judgment was 0 .922 ,APACHE Ⅱ score of 21 .2 was the best diagnostic point ,the sensitivity was 95% ,and specificity was 89% . Conclusion The APACHE Ⅱscore could predict severity of patients with Severe acute organophosphorus poisoning ,and APACHEⅡscore ≥21 .2 could be used as the prognosis for death of the patients .