检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2014年
17期
2387-2388
,共2页
三维适形放疗%化疗%Ⅲ期非小细胞肺癌
三維適形放療%化療%Ⅲ期非小細胞肺癌
삼유괄형방료%화료%Ⅲ기비소세포폐암
three-dimensional conformal radiation therapy%chemotherapy%non-small cell lung cancer at stage Ⅲ
目的:探讨三维适形放疗联合化疗治疗Ⅲ期非小细胞肺癌的临床效果。方法将2011年3月至2013年3月于本院治疗的120例Ⅲ期非小细胞肺癌患者分为对照组与观察组。对照组给予传统放疗联合化疗,观察组给予三维适形放疗联合化疗。比较两组患者的疗效及不良反应发生情况。结果两组患者近期疗效总控制率以及放疗40 Gy时、放疗结束时、放疗结束后1个月肌钙蛋白水平比较差异均有统计学意义( P<0.05)。治疗后放射性食管炎、放射性肺炎发生率组间比较差异无统计学意义(P>0.05)。结论三维适形放疗联合化疗治疗Ⅲ期非小细胞肺癌能够提高近期疗效,避免心肌损伤,但存在一定程度的急性不良反应。
目的:探討三維適形放療聯閤化療治療Ⅲ期非小細胞肺癌的臨床效果。方法將2011年3月至2013年3月于本院治療的120例Ⅲ期非小細胞肺癌患者分為對照組與觀察組。對照組給予傳統放療聯閤化療,觀察組給予三維適形放療聯閤化療。比較兩組患者的療效及不良反應髮生情況。結果兩組患者近期療效總控製率以及放療40 Gy時、放療結束時、放療結束後1箇月肌鈣蛋白水平比較差異均有統計學意義( P<0.05)。治療後放射性食管炎、放射性肺炎髮生率組間比較差異無統計學意義(P>0.05)。結論三維適形放療聯閤化療治療Ⅲ期非小細胞肺癌能夠提高近期療效,避免心肌損傷,但存在一定程度的急性不良反應。
목적:탐토삼유괄형방료연합화료치료Ⅲ기비소세포폐암적림상효과。방법장2011년3월지2013년3월우본원치료적120례Ⅲ기비소세포폐암환자분위대조조여관찰조。대조조급여전통방료연합화료,관찰조급여삼유괄형방료연합화료。비교량조환자적료효급불량반응발생정황。결과량조환자근기료효총공제솔이급방료40 Gy시、방료결속시、방료결속후1개월기개단백수평비교차이균유통계학의의( P<0.05)。치료후방사성식관염、방사성폐염발생솔조간비교차이무통계학의의(P>0.05)。결론삼유괄형방료연합화료치료Ⅲ기비소세포폐암능구제고근기료효,피면심기손상,단존재일정정도적급성불량반응。
Objective To explore clinical efficacy of simultaneous chemotherapy and three dimensional confor-mal radiation therapy in treating patients with non-small cell lung cancer at stage Ⅲ .Methods A total of 120 pa-tients with non-small cell lung cancer at Ⅲ stage ,treated in this hospital from Mar .2011 to Mar .2013 ,were divided into control group ,receiving conventional radiotherapy and chemotherapy ,and observation group ,receiving three-di-mensional conformal radiotherapy and chemotherapy .Curative efficacy and incidence of adverse events were compared between the two groups .Results Total control rate ,and levels of troponin detected at radiation therapy of 40 Gy ,at the end of radiotherapy and one month after radiotherapy were with statistical between the two groups (P<0 .05) . Incidence rates of radioactive esophagitis and radioactive pneumonia were without significant differences (P>0 .05) . Conclusion Application of combined chemotherapy and three-dimensional conformal radiotherapy for the treating of non-small cell lung cancer at Ⅲ stage could improve recent efficacy and avoid myocardial injury ,but might be with a-cute adverse events .